Organ dose in cardiac dual?energy computed tomography: a Monte　Carlo study

摘要

Dual-energy computed tomography (DECT) has appeared as a novel approach with the aim of evaluating artery-related diseases. With the advent of DECT, concerns have been raised about the induction of diseases such as cancer due to high radiation exposure of patients. Therefore, the dose received by patients in DECT should be considered. The parameter most commonly used for patient dosimetry is the effective dose (ED). The purpose of this study is to model and validate a DECT scanner by a developed MCNP Monte Carlo code and to calculate the organ doses, the ED, and the conversion factor (k-factor) used in determining ED in the cardiac imaging protocol. To validate the DECT scanner simulation, a standard dosimetry body phantom was modeled in two radiation modes of single energy CT and DECT. The results of simulated CT dose index (CTDI) were compared with those of ImPACT or measurement data. Then dosimetry phantom was replaced by the male and female ORNL phantoms and the organ doses were calculated. The organ doses were also calculated by ImPACT dose software. In the initial validation stage, the minimum and maximum observed relative differences between results of MNCP simulation and measured were 2.77% and 5.79% for the central CTDI and 1.91% and 5.83% for the averaged peripheral CTDI, respectively. The mean ED of simulation and the ImPACT were 3.23 and 5.55 mSv/100 mAs, and the mean k-factor was 0.016 and 0.032 mSv mGy(-1) cm(-1) in the male and female phantoms, respectively. The k-factor obtained for males is close to the currently used k-factor, but the k-factor for females is almost twice.