MRD in AML: time for redefinition of CR?

摘要

Currently, the most important prognostic factors for AML are based on cytogenetics and molecular abnormalities, which are assessed at diagnosis.2 Although these factors have been shown to be of utmost importance in risk stratification, the treatment outcome of patients within the thus-defined risk groups is still highly variable. New prognostic factors that, apart from diagnosis parameters, may include treatment and response related factors are needed.