HPV testing as a screen for cervical cancer

摘要

Cervical cancer is a leading cause of death in women worldwide, with 530 000 new cases and 275 000 deaths worldwide each year. Cervical cancer is preventable because it has a long pre-invasive phase and is easily identified by clinical and histopathological examination. This review summarizes the current knowledge of human papillomavirus (HPV) related premalignant and malignant disease and the studies that have led to the recommendation of HPV testing as a primary screening test.