D-Ribose Enhances the Identification of Hibernating Myocardium

摘要

Hibernating myocardium describes a persistent state of reduced left ventricular (LV) function associated with reduced blood flow. The reduction of flow and function may result from chronic, repetitive ischemia. Modalities used for detection of hibernating myocardium include positron emission tomography (PET), dobutamine stress echocardiography (DSE), and perfusion imaging using single photon emission computerized tomography (SPECT). PET imaging using radiolabelled fluorodeoxy-glucose has been reported to be the most sensitive method for the detection of hibernating myocardium [1]. However, PET is not universally available; therefore, SPECT and DSE are the most commonly used techniques. Both techniques have >80°/o sensitivity for detection of hibernating myocardium but false-negative studies are not uncommon.