Recombinant Antibodies for In Vivo Research Launched

摘要

Absolute Antibody Ltd has announced the launch of its VivopureX~TM recombinant mouse antibodies for in vivoresearch in mouse models.The collection consists of popular antibody clones,many originally obtained from rats or hamsters,which Absolute Antibody has engineered into mouse-anti-mouse recombinant versions to improve research results.The antibodies are all available in discounted bulk sizes ranging from 1 mg to 100 mg.VivopureX~TM antibodies are species-matched chimeric antibodies,consisting of a clone's original antigen-binding variable domain with a mouse constant domain,which means they do not induce neutralising antibodies in mouse models.As a result,the engineered recombinant antibodies offer many advantages compared to the original monoclonal antibodies,including increased long-term efficacy,stronger potency and a more consistent response across cohorts.In addition,VivopureX~TM antibodies feature engineered effector functions,with Fc receptor binding tailored to best suit popular applications such as depletion,agonism or blocking.