Engineered Knockout Cell Lysates for Reproducible Proteomic Analysis

摘要

Abcam's new engineered knockout cell lysates enable proteomic studies by providing researchers with’true negative’controls.Acquiring reliable off-the-shelf knockout mouse models or cell lines that match specific experimental requirements can be challenging,and often need to be sourced directly tfrom individual researchers or labs.Abcam's newly-launched collection addresses this issue by providing access to over 2,800 diploid KO cell lysates,the largest selection currently available to researchers.The lysates are useful for studies requiring loss-of-function phenotypes at the proteomic level as well as routine applications such as Western blotting and mass spectroscopy.They also can be used to support antibody and target validation.The use of diploid cells makes the lysates well suited to the more complex studies often carried out in cancer research.