Bipyridine Facilitates Regioselective Dimerization of Alkynes in the Absence of Transition Metal

摘要

We herein present a transition metal free protocol for the dimerization of terminal aryl alkynes to prepare enyne deriva- tives using potassium tert-butoxide in the presence of catalytic amount of 2,2’-bipyridine. The reaction is compatible with a wide range of substrates resulting in high to moderate yields of the corresponding head-to-head dimers with E-selectivity.