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A donor's a person, no matter how small

机译:捐助者是一个人,无论多么小

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摘要

The work is long overdue. In the midst of our focus on improving outcomes of their sicker siblings, we have too-long neglected what should be an ongoing task of ensuring that we (1) know in detail current common and rare risks of these procedures and (2) work to minimize or eliminate side-effects in these healthy children as they go through the BM or peripheral blood stem cell (PBSC) collection process. This study confirms our long-held belief that BM and PBSC collection from minor donors is generally safe, resulting in temporary discomfort in a portion of donors (only 1 severe adverse event [nonlife-threatening] was reported in 453 donations). This distinguishes BM and PBSC donation from riskier sibling solid organ donation, counter to a recent American Academy of Pediatrics policy statement that calls for BM/PBSC and solid organ donors to be approached in a similar fashion.
机译:这项工作早就该完成了。在专注于改善其患病兄弟姐妹的结局的过程中,我们长期以来一直在忽略确保我们(1)详细了解这些程序目前常见和罕见的风险,以及(2)在他们通过BM或外周血干细胞(PBSC)收集过程中,将这些健康儿童的副作用减至最小或消除。这项研究证实了我们长期以来的信念,即从较小的捐献者那里收集BM和PBSC通常是安全的,从而导致部分捐献者暂时感到不适(在453笔捐献中仅报告了1次严重不良事件[不危及生命])。这与将BM和PBSC捐赠与风险更高的同胞实体器官捐赠区分开来,这与美国儿科学会最近的政策声明相反,该声明要求以类似方式联系BM / PBSC和实体器官捐赠者。

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