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Gene diversity and biochemical markers among someMuslim Populations of Uttar Pradesh

机译:北方邦一些穆斯林人群的基因多样性和生化标记

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A sample of 312 individuals belonging to Sheikh (80), Pathan (54), Ansari (82),Syed (33), Saifi (33) and Hindu Bania (30) populations were surveyed for four protein andthree enzyme loci comprising 12 alleles. The markers used were protein (transferrin, hapto-globin, haemoglobin) and enzyme (lactate dehydrogenase, phosphogluconate dehydroge-nase, adenylate kinase). Except caeruloplasmin, variants were found among all loci, thoughno rare variant appears. The populations show genetic equilibrium for all of the loci. Ourgene frequencies show some difference from earlier studies for Muslims in general, therebeing no biradari wise study among Sunni Muslims earlier done anywhere in India or abroad.Heterozygosity ranged from 0.0123 to 0.1994 (Sheikh), 0.0182 to 0.2046 (Pathan), 0.0239 to0.1844 (Ansari), 0.0587 to 0.3966 (Syed), 0 to 0.3909 (Bania); the average DST and GSTvalues for the seven marker loci were 0.001 032 and 0.00 879, respectively. The results arediscussed. The gene frequency study shows closer relationship of Ansaris and Saifis withnative Hindu Banias, and may reflect on their probable conversion in the not remote past.
机译:对来自Sheikh(80),Pathan(54),Ansari(82),Syed(33),Saifi(33)和Hindu Bania(30)种群的312名个体进行了抽样调查,以调查包括12个等位基因的四个蛋白质和三个酶基因座。所使用的标记是蛋白质(转铁蛋白,触珠蛋白,血红蛋白)和酶(乳酸脱氢酶,磷酸葡糖酸脱氢酶,腺苷酸激酶)。除了caeruloplasmin,所有基因座中都发现了变体,尽管没有罕见的变体出现。种群显示所有基因座的遗传平衡。我们的基因频率与一般的早期穆斯林研究有所不同,在印度或国外任何地方的较早逊尼派穆斯林中均未进行过比拉达瑞明智的研究。杂合度范围为0.0123至0.1994(谢赫),0.0182至0.2046(Pathan),0.0239至0.1844 (Ansari),0.0587至0.3966(Syed),0至0.3909(Bania);七个标记位点的平均DST和GST值分别为0.001 032和0.00 879。讨论了结果。基因频率研究显示了Ansaris和Saifis与原生印度教Banias的密切关系,并可能反映了它们在不遥远的过去中可能的转换。

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