N-Arylation of Nitrogen-Containing Heterocycles with Cu(II) Complex of 4-(2,2’:6’,2“-Terpyridin-4’-yl)toluene as a Versatile and Efficient Catalyst

摘要

Copper(II) complex of 4-(2,2’:6’,2“-terpyridin-4’-yl)toluene(ttpy) was found to be a profitable catalyst for the N-arylation of a variety of nitrogen-containing heterocycles, such as some kinds of azoles and a secondary aliphatic amine, with aryl halides (iodides, bromides, and chlorides) under moderate conditions. A variety of functionalized aryl halides were tolerated in good to excellent yields by this air stable and low cost Cu(II)-based catalytic system. Phenyl boronic acid was also used as an alternative to aryl halides to supply aryl moiety.