Tandem Oxidative Pudovik Reaction Using Fe3O4@SiO2-Metformin-Cu (II) as an Efficient and Recoverable Catalyst

摘要

One-pot condensation of benzyl alcohol with di-alkyl/ aryl phosphite under free solvent conditions was investigated in the presence of Fe3O4@SiO2-Met-Cu (II) as a recyclable heterogeneous catalyst and aqueous tert-butyl hydroperoxide (TBHP) as the oxidant. The advantages of this protocol include good to excellent yields, easy workup, short reaction time and good reusability to 4 cycles. Also, interactions between metal and ligand in the Fe3O4@SiO2-Metformin complex is studied by using theoretical calculations