PPh3 Catalyzed Post-Transformation Ugi-4CR Intramolecular Cyclization Reaction: One-Pot Synthesis of Functionalized Spiropyrrolidinochromanones

摘要

Stereoselective post-transformation of Ugi-4CR approach lead- ing to synthesis of functionalized spiropyrrolidinochromanones via PPh3 catalysed intramolecular cyclization. In addition, one major finding was that, the solvent play the role of nucleophile, thus providing a highly atom economical and environmentally benign approach towards the synthesis of spiropyrrolidinochro- manones.