Graphene Oxide Pickering Emulsion-A Novel Reaction Medium for the Synthesis of 2-Aminothiazole

摘要

In the present study,a novel protocol for the synthesis of 2-aminothiazoles has been developed using a graphene oxide(GO)stabilized Pickering emulsion system.GO was prepared by the modified Hummer‘s method and characterized with XRD,FTIR,UV-Visible spectroscopy,TGA and DLS techniques.The size of the o/w emulsion droplets stabilized by GO were determined using a polarized optical microscope.The emulsion system was used for the synthesis of 2-aminothiazole by Hantzsch reaction.The Reactions were carried out at room temperature and under static condition,without stirring.The application of the reaction system were extended to substituted phenacyl bromides and about 93% of the corresponding 2-aminothiazole derivative was obtained in 3 h.