Synthesis of 1,6-Naphthyridine and Its Derivatives: A Systematic Review

摘要

The naturally and synthetically obtained 1,6-naphthyridine derivatives possess a wide range of pharmacological properties. This factor inspired the medicinal chemists and organic chemists to develop new methods for the synthesis of 1,6- naphthyridine derivatives. This review will discuss the synthesis of 1,6-naphthyridine and its derivatives from diverse starting materials or key intermediates in a systematic manner with appropriate mechanisms.