Bifunctional Self-Powered Drug Delivery System to Promote the Release and Transdermal Delivery of Polar Molecules

摘要

Electrical stimulation to enhance molecular release and trans- dermal drug delivery has aroused extensive research and clinical medical interest owing to its unique advantages such as being stimuli-responsive, sensitive, flexible, and controllable. Herein, a self-powered system driven by piezoelectric substrate is designed to promote the release and transdermal delivery of polar molecules. Notedly, the electric signals generated by piezoelectric substrate contribute to trigger the electric- responsive drug release and transdermal drug delivery.