Convenient Hydrophosphorylation of Dibenzo[b,f][1,4]oxa-/thiazepines by Acid Catalysis

摘要

A protocol for the acid-catalyzed synthesis of phosphorylated dihydrodibenzoxa-/thiazepine derivatives from dibenzo[b,f][1,4]oxa-/thiazepines has been established. The reaction appears compatible with a range of functional groups in both the dibenzo[b,f][1,4]oxa-/thiazepine, H-phosphonate and especially diarylphosphine oxide phosphorylation partners, affording moderate to excellent yields of the corresponding products. The present method further expands the utility of Pudovik reaction.