Comprehensive Evaluation of Cryopreserved Bone-Derived Osteoblasts for the Repair of Segmental Mandibular Defects in Canines

摘要

BackgroundThe repair of segmental mandibular defects remains challenging in the clinic. Previous studies have shown that cryopreserved bone-derived osteoblasts (CBOs) have good proliferation and osteogenicity. However, whether these cells can be used in the repair of segmental mandibular defects is largely unknown.