Is it still cool to cool? Interpreting the latest hypothermia for cardiac arrest trial: March 2014 annals of emergency medicine journal club

摘要

1. The authors reference 2 previous trials that compared therapeutic hypothermia (32degC to 34degC [89.6F to 93.2F] for 12 to 24 hours) with standard treatment and "showed a significant improvement in neurologic function and survival with therapeutic hypothermia."A What was the treatment effect in the previous 2 studies? What percentage of patients had neurologically intact survival? How many patients would one need to treat with hypothermia to produce 1 additional neurologically intact patient.