Proton pump inhibitor side effects and drug interactions: much ado about nothing?

Madanick RD

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Proton pump inhibitor side effects and drug interactions: much ado about nothing?

机译：质子泵抑制剂的副作用和药物相互作用：事不宜迟？

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Proton pump inhibitors (PPIs) are widely prescribed for acid-peptic disease. In general, the safety of this class of drugs has been excellent. However, in the past several years, epidemiologic studies have indicated possible risks that are biologically plausible.

机译：质子泵抑制剂（PPI）被广泛指定用于胃酸消化系统疾病。通常，这类药物的安全性非常好。然而，在过去的几年中，流行病学研究表明可能存在生物学上合理的风险。

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《Cleveland Clinic journal of medicine》 |2011年第1期|共11页
作者
Madanick RD;
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正文语种 eng
中图分类预防医学、卫生学;
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1. Proton pump inhibitor side effects and drug interactions: much ado about nothing? [J] . Madanick RD Cleveland Clinic journal of medicine . 2011,第1期

机译：质子泵抑制剂的副作用和药物相互作用：事不宜迟？
2. Effects of proton pump inhibitors and famotidine on elimination of plasma methotrexate: Evaluation of drug–drug interactions mediated by organic anion transporter 3 [J] . Narumi Katsuya, Sato Yu, Kobayashi Masaki, Biopharmaceutics and Drug Disposition . 2017,第9期

机译：质子泵抑制剂与法替辛对血浆甲氨蝶呤消除的影响：有机阴离子转运蛋白介导的药物 - 药物相互作用评价
3. A clinical drug-drug interaction study to evaluate the effect of a proton-pump inhibitor, a combined P-glycoprotein/cytochrome 450 enzyme (CYP)3A4 inhibitor, and a CYP2C9 inhibitor on the pharmacokinetics of vismodegib [J] . Malhi Vikram, Colburn Dawn, Williams Sarah J., Cancer chemotherapy and pharmacology. . 2016,第1期

机译：临床药物相互作用研究，评估质子泵抑制剂，P-糖蛋白/细胞色素450酶（CYP）3A4组合抑制剂和CYP2C9抑制剂对vismodegib药代动力学的影响
4. UColorado_SOM: Extraction of Drug-Drug Interactions from BioMedical Text using Knowledge-rich and Knowledge-poor Features [C] . Negacy D. Hailu, Lawrence E. Hunter, K. Bretonnel Cohen 7th International workshop on semantic evaluation . 2013

机译：UColorado_SOM：使用知识丰富和知识匮乏的特征从生物医学文本中提取药物相互作用
5. Implementation of an Evidence-Based Clinical Decision Tool to Improve Guideline Adherence and Drug Dosing Accuracy of Proton Pump Inhibitors in the Hospital Setting [D] . Morris, Kathleen E. 2019

机译：实施基于证据的临床决策工具，以提高医院环境中质子泵抑制剂的指南依从性和药物剂量准确性
6. A clinical drug–drug interaction study to evaluate the effect of a proton-pump inhibitor a combined P-glycoprotein/cytochrome 450 enzyme (CYP)3A4 inhibitor and a CYP2C9 inhibitor on the pharmacokinetics of vismodegib [O] . Vikram Malhi, Dawn Colburn, Sarah J. Williams, -1

机译：临床药物相互作用研究评估质子泵抑制剂P-糖蛋白/细胞色素450酶（CYP）3A4组合抑制剂和CYP2C9抑制剂对vismodegib药代动力学的影响
7. A clinical drug–drug interaction study to evaluate the effect of a proton-pump inhibitor, a combined P-glycoprotein/cytochrome 450 enzyme (CYP)3A4 inhibitor, and a CYP2C9 inhibitor on the pharmacokinetics of vismodegib [O] . Vikram Malhi, Dawn Colburn, Sarah J. Williams, 2016

机译：临床药物相互作用研究，评估质子泵抑制剂，P-糖蛋白/细胞色素450酶（CYP）3A4组合抑制剂和CYP2C9抑制剂对vismodegib药代动力学的影响

Proton pump inhibitor side effects and drug interactions: much ado about nothing?

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