首页> 外文期刊>Annals of vascular surgery >Anatomic suitability of ruptured abdominal aortic aneurysms for endovascular repair.
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Anatomic suitability of ruptured abdominal aortic aneurysms for endovascular repair.

机译:腹主动脉瘤破裂的血管内修复的解剖学适应性。

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摘要

Mortality from ruptured abdominal aortic aneurysms (rAAAs) remains high despite improvements in anesthesia, postoperative intensive care, and surgical techniques. Recent small series and single-center experiences suggest that endovascular aneurysm repair (EVAR) for rAAAs is feasible and may improve short-term survival. However, the applicability of EVAR to all cases of rAAA is unknown. The purpose of this study was to investigate the anatomical suitability of ruptured aneurysms for EVAR as determined by preoperative cross-sectional imaging. A contemporary consecutive series of rAAAs presenting to a tertiary academic center was retrospectively reviewed. Preoperative radiographic imaging was reviewed and assessed for endovascular compatibility based on currently available EVAR devices. Patients with aneurysm morphology demonstrating neck diameter >32 mm, neck length <10 mm, neck angulation >60 degrees, severe iliac tortuosity, or external iliac diameter <6 mm were deemed noncandidates for EVAR. Forty-seven rAAAs were treated over a 10-year period, with 47% of patients presenting with free rupture and 60% of patients transferred from outside hospitals. Five (11%) patients were treated with EVAR, all over the past 2 years, while the remaining 42 patients underwent open repair. Preoperative imaging was available for review in 43 (91%) patients, and morphological measurements indicated that 49% would have been candidates for EVAR with currently available devices. Criteria precluding EVAR in this cohort were inadequate neck length in 73%, unsuitable iliac access in 23%, large neck diameter in 18%, and severe neck angulation in 14%. Overall 30-day mortality was 34%, and 1-year mortality was 42%. Candidates for EVAR were more likely than non-EVAR candidates to be male (95% vs. 68%, p = 0.046) and to have smaller sac diameters (7.0 vs. 8.5 cm, p = 0.02) and longer neck lengths (24.1 vs. 8.6 mm, p < 0.0001); less likely to have a >60 degree angulated neck (10% vs. 45%, p = 0.0002), larger external iliac diameter (8.9 vs. 7.3 mm, p = 0.015), and less blood loss during surgical repair (2.4 vs. 6.0 L, p = 0.02); and more likely to be discharged home (71% vs. 25%, p = 0.05). There were no differences in 30-day, 1-year, or overall mortality between candidates for EVAR and noncandidates. Only 49% of patients with rAAAs in this consecutive series were found to be candidates for EVAR with conventional stent-graft devices. Differences in demographics, aneurysm morphology, and outcomes between candidates and noncandidates undergoing open repair suggest that differential risks apply to ruptured aneurysm patients. Protocols and future reports of EVAR for rAAAs should be tailored to these results. Device and technique modifications are necessary to increase the applicability of EVAR for rAAAs.
机译:尽管麻醉,术后重症监护和手术技术有所改善,但腹主动脉瘤破裂引起的死亡率仍然很高。最近的小系列和单中心经验表明,rAAAs的血管内动脉瘤修复(EVAR)是可行的,并且可以提高短期生存率。但是,EVAR是否适用于所有rAAA情况仍然未知。这项研究的目的是调查术前横截面成像确定的破裂动脉瘤对EVAR的解剖学适应性。回顾性地回顾了当代向大专学术中心展示的一系列rAAAs。根据当前可用的EVAR设备,对术前影像学检查进行了评估并评估了血管内相容性。动脉瘤形态表明颈部直径> 32 mm,颈部长度<10 mm,颈部角度> 60度,骨曲折严重或external骨外直径<6 mm的患者被认为是EVAR的非候选者。 10年内共治疗了47例rAAAs,其中47%的患者表现为自由破裂,60%的患者从医院外转移。在过去的两年中,有五名(11%)患者接受了EVAR治疗,而其余42例患者接受了开放式修复。术前影像学可用于43例(91%)患者中,并且形态学测量表明49%的患者将使用当前可用的设备进行EVAR。在该队列中,排除EVAR的标准是:颈部长度不足(73%),通道不适当(23%),大颈部直径(18%)和严重的颈部成角度(14%)。总的30天死亡率为34%,而1年死亡率为42%。与非EVAR候选者相比,EVAR候选者更可能是男性(95%对68%,p = 0.046),囊直径更小(7.0对8.5 cm,p = 0.02)和脖子长度更长(24.1对8.6毫米,p <0.0001);颈部角度> 60度的可能性较小(10%对45%,p = 0.0002),larger外直径较大(8.9对7.3 mm,p = 0.015),并且在手术修复过程中失血少(2.4 vs. 6.0 L,p = 0.02);更有可能出院(71%vs. 25%,p = 0.05)。 EVAR候选人和非候选人在30天,1年或总死亡率方面没有差异。在该连续系列中,只有49%的rAAAs患者被选为使用常规支架植入设备进行EVAR的候选人。接受开放修补的候选人与非候选人之间在人口统计学,动脉瘤形态和结局方面的差异表明,破裂性动脉瘤患者存在不同的风险。应针对这些结果量身定制用于rAAA的EVAR的协议和未来报告。必须进行设备和技术修改才能提高EVAR对rAAA的适用性。

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