Germline PAX5 mutation predisposes to familial B-cell precursor acute lymphoblastic leukemia

Duployez Nicolas; Jamrog Laura A.; Fregona Vincent; Hamelle Camille; Fenwarth Laurene; Lejeune Sophie; Helevaut Nathalie; Geffroy Sandrine; Caillault Aurelie; Marceau-Renaut Alice; Poulain Stephanie; Roche-Lestienne Catherine; Largeaud Laetitia; Prade Nais; Dufrechou Stephanie; Hebrard Sylvie; Berthon Celine; Nelken Brigitte; Fernandes Jose; Villenet Celine; Figeac Martin; Gerby Bastien; Delabesse Eric; Preudhomme Claude; Broccardo Cyril

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Germline PAX5 mutation predisposes to familial B-cell precursor acute lymphoblastic leukemia

机译：种系PAX5突变易于家族性B细胞前体急性淋巴细胞白血病

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《Blood: The Journal of the American Society of Hematology》 |2021年第10期|共5页
作者
Duployez Nicolas; Jamrog Laura A.; Fregona Vincent; Hamelle Camille; Fenwarth Laurene; Lejeune Sophie; Helevaut Nathalie; Geffroy Sandrine; Caillault Aurelie; Marceau-Renaut Alice; Poulain Stephanie; Roche-Lestienne Catherine; Largeaud Laetitia; Prade Nais; Dufrechou Stephanie; Hebrard Sylvie; Berthon Celine; Nelken Brigitte; Fernandes Jose; Villenet Celine; Figeac Martin; Gerby Bastien; Delabesse Eric; Preudhomme Claude; Broccardo Cyril;
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作者单位

Ctr Hosp Univ CHU Lille Biol &

Pathol Ctr Hematol Lab Lille France;

Univ Toulouse III Paul Sabatier Ctr Rech Cancerol Toulouse INSERM UMR 1037 Toulouse France;

Univ Toulouse III Paul Sabatier Ctr Rech Cancerol Toulouse INSERM UMR 1037 Toulouse France;

Univ Toulouse III Paul Sabatier Ctr Rech Cancerol Toulouse INSERM UMR 1037 Toulouse France;

Ctr Hosp Univ CHU Lille Biol &

Pathol Ctr Hematol Lab Lille France;

CHU Lille Jeanne de Flandre Hosp Dept Clin Genet Lille France;

Ctr Hosp Univ CHU Lille Biol &

Pathol Ctr Hematol Lab Lille France;

Ctr Hosp Univ CHU Lille Biol &

Pathol Ctr Hematol Lab Lille France;

Ctr Hosp Univ CHU Lille Biol &

Pathol Ctr Hematol Lab Lille France;

Ctr Hosp Univ CHU Lille Biol &

Pathol Ctr Hematol Lab Lille France;

Ctr Hosp Univ CHU Lille Biol &

Pathol Ctr Hematol Lab Lille France;

INSERM U1277 Lille France;

Univ Toulouse III Paul Sabatier Ctr Rech Cancerol Toulouse INSERM UMR 1037 Toulouse France;

Univ Toulouse III Paul Sabatier Ctr Rech Cancerol Toulouse INSERM UMR 1037 Toulouse France;

Univ Toulouse III Paul Sabatier Ctr Rech Cancerol Toulouse INSERM UMR 1037 Toulouse France;

Univ Toulouse III Paul Sabatier Ctr Rech Cancerol Toulouse INSERM UMR 1037 Toulouse France;

INSERM U1277 Lille France;

CHU Lille Jeanne de Flandre Hosp Dept Pediat Hematol Lille France;

Ctr Hosp Valenciennes Dept Clin Hematol Valenciennes France;

Univ Lille Funct Genom Platform Lille France;

Univ Lille Funct Genom Platform Lille France;

Univ Toulouse III Paul Sabatier Ctr Rech Cancerol Toulouse INSERM UMR 1037 Toulouse France;

Univ Toulouse III Paul Sabatier Ctr Rech Cancerol Toulouse INSERM UMR 1037 Toulouse France;

Ctr Hosp Univ CHU Lille Biol &

Pathol Ctr Hematol Lab Lille France;

Univ Toulouse III Paul Sabatier Ctr Rech Cancerol Toulouse INSERM UMR 1037 Toulouse France;

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原文格式 PDF
正文语种 eng
中图分类血液及淋巴系疾病;
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1. Individualized leukemia cell-population profiles in common B-cell acute lymphoblastic leukemia patients [J] . Jian-Hua Yu, Jing-Tao Dong, Yong-Qian Jia, 癌症（英文版） . 2013,第004期
2. Advances in the development of chimeric antigen receptor-T-cell therapy in B-cell acute lymphoblastic leukemia [J] . Xian Zhang, Jing-Jing Li, Pei-Hua Lu 中华医学杂志（英文版） . 2020,第004期
3. PAX5 P80R mutation identifies a novel subtype of B-cell precursor acute lymphoblastic leukemia with favorable outcome (vol 133, pg 280, 2019) [J] . Blood: The Journal of the American Society of Hematology . 2020,第22期

机译：PAX5 P80R突变鉴定了具有有利结果的B细胞前体急性淋巴细胞白血病的新型亚型（Vol 133，PG 280,2019）
4. PAX5 P80R mutation identifies a novel subtype of B-cell precursor acute lymphoblastic leukemia with favorable outcome [J] . Passet Marie, Boissel Nicolas, Sigaux Francois, Blood: The Journal of the American Society of Hematology . 2019,第3期

机译：PAX5 P80R突变鉴定了具有有利结果的B细胞前体急性淋巴细胞白血病的新型亚型
5. PAX5 mutations occur frequently in adult B-cell progenitor acute lymphoblastic leukemia and PAX5 haploinsufficiency is associated with BCR-ABL1 and TCF3-PBX1 fusion genes: a GRAALL study [J] . J Familiades, M Bousquet, M Lafage-Pochitaloff, Leukemia . 2009,第11期

机译：GRAALL研究表明，PAX5突变在成人B细胞祖细胞急性淋巴细胞白血病中频繁发生，并且PAX5单倍功能不足与BCR-ABL1和TCF3-PBX1融合基因相关。
6. Classification of B-Cell Acute Lymphoblastic Leukemia Microscopic Images Using Crow Search Algorithm [C] . N.Bharanidharan, Harikumar Rajaguru International Conference on Biomedical Engineering . 2021

机译：使用乌鸦搜索算法进行B细胞急性淋巴细胞白血病微观图像的分类
7. Deciphering the role of microRNA-708 in precursor B-cell acute lymphoblastic leukemia biology. [D] . Doshi, Kshama. 2012

机译：解读microRNA-708在前体B细胞急性淋巴细胞白血病生物学中的作用。
8. Heterozygous carriers of germline c.657_661del5 founder mutation in NBN gene are at risk of central nervous system relapse of B-cell precursor acute lymphoblastic leukemia [O] . Bartłomiej Tomasik, Agata Pastorczak, Wojciech Fendler, 2018

机译：NBN基因种系c.657_661del5建立者突变的杂合子携带者有中枢神经系统复发的风险B细胞前体是急性淋巴细胞性白血病
9. PAX5 mutations occur frequently in adult B-cell progenitor acute lymphoblastic leukemia and PAX5 haploinsufficiency is associated with BCR-ABL1 and TCF3-PBX1 fusion genes: a GRAALL study [O] . Familiades, J, Bousquet, M, Lafage-Pochitaloff, M, 2009

机译：GRAALL研究表明，PAX5突变在成人B细胞祖细胞急性淋巴细胞白血病中频繁发生，并且PAX5单倍功能不足与BCR-ABL1和TCF3-PBX1融合基因相关。

Germline PAX5 mutation predisposes to familial B-cell precursor acute lymphoblastic leukemia

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