Durability of Fecal Microbiota Transplantation for C difficile Infection

摘要

In a retrospective study of patients who underwent FMT and had continued risks for Clostridioides difficile disease, antibiotic exposure was the only significant risk factor for recurrence. Observational studies have indicated a 90% cure rate with fecal microbiota transplantation (FMT) for cases of recurrent Clostridioides difficile infection (CDI). FMT has been postulated to work by restoring a diverse microbiological fecal milieu. If such a change occurs after FMT, an important question is how long does it last. That is, what is its durability?