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Early Experience with HIV+ Kidney and Liver Organ Donation

机译:早期经验艾滋病毒+肾脏和肝脏器官捐赠

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摘要

Thirty-five kidney and 19 liver programs developed approved protocols (25% have not listed any candidates), and by the end of 2018,102 HIV+ recipients received 71 kidneys and 31 livers from 50 deceased donors with positive HIV screens (estimated false positive rate, 40%-50%). Two recipient deaths (multisystem organ failure and aspiration), one thrombosis-related graft failure, and three rejections were reported. Too few patients with at least 1 year of posttrans-plant follow-up were available for reliable statistical comparison with a non-HIV cohort, but no obvious safety concerns were identified.
机译:35个肾脏和19个肝脏项目制定了经批准的方案(25%未列出任何候选方案),截至2018102年底,HIV+患者从50名HIV筛查阳性的已故捐赠者那里获得了71个肾脏和31个肝脏(估计假阳性率为40%-50%)。报告了两例受者死亡(多系统器官衰竭和误吸)、一例血栓相关移植物衰竭和三例排斥反应。很少有患者进行了至少1年的移植后随访,可以与非HIV队列进行可靠的统计比较,但没有发现明显的安全问题。

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