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Dosimetric models of the eye and lens of the eye and their use in assessing dose coefficients for ocular exposures

机译:眼睛和眼睛晶状体的剂量模型及其在评估眼睛暴露的剂量系数中的用途

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Based upon recent epidemiological studies of ocular exposure, the Main Commission of the International Commission on Radiological Protection (ICRP) in ICRP Publication 118 states that the threshold dose for radiation-induced cataracts is now considered to be approximately 0.5 Gy for both acute and fractionated exposures. Consequently, a reduction was also recommended for the occupational annual equivalent dose to the lens of the eye from 150 mSv to 20 mSv, averaged over defined periods of 5 years. To support ocular dose assessment and optimisation, Committee 2 included Annex F within ICRP Publication 116. Annex F provides dose coefficients - absorbed dose per particle fluence - for photon, electron, and neutron irradiation of the eye and lens of the eye using two dosimetric models. The first approach uses the reference adult male and female voxel phantoms of ICRP Publication 110. The second approach uses the stylised eye model of Behrens et al., which itself is based on ocular dimensional data given in Charles and Brown. This article will review the data and models of Annex F with particular emphasis on how these models treat tissue regions thought to be associated with stem cells at risk.
机译:根据最近的眼部暴露流行病学研究,国际放射防护委员会(ICRP)主委员会在ICRP出版物118中指出,对于急性和分次暴露,辐射诱发性白内障的阈值剂量现在被认为约为0.5 Gy 。因此,还建议将眼球的年度职业等效剂量从150毫希沃特降低到20毫希沃特,在定义的5年中平均。为支持眼睛剂量评估和优化,第2委员会将附件F纳入了ICRP出版物116中。附件F提供了剂量系数-使用两个剂量学模型对眼睛和晶状体进行光子,电子和中子辐射的每粒子注量的吸收剂量。第一种方法使用ICRP出版物110中的参考成人和女性体素体模。第二种方法使用Behrens等人的程式化眼睛模型,该模型本身是基于Charles和Brown给出的眼图数据。本文将回顾附录F的数据和模型,特别着重于这些模型如何处理被认为与处于危险中的干细胞相关的组织区域。

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