Local immunosuppression in vascularized composite allotransplantation (VCA): A systematic review

Safi Ali-Farid; Kauke Martin; Nelms Laurel; Palmer William Jackson; Tchiloemba Bianief; Kollar Branislav; Haug Valentin; Pomahac Bohdan

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Local immunosuppression in vascularized composite allotransplantation (VCA): A systematic review

机译：血管化复合分征性分子普通植物（VCA）的局部免疫抑制：系统审查

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Background: Local immunosuppression in vascularized composite allotransplantation (VCA) aims to minimize immunosuppressant-related toxic and malignant side effects. Promising allograft survival data have been published by multiple workgroups. In this systematic review, we examine preclinical animal studies that investigated local immunosuppression in VCA.

机译：背景：血管化复合同种异体移植（VCA）中的局部免疫抑制旨在将免疫抑制剂相关的毒副作用和恶性副作用降至最低。多个工作组已经公布了有希望的同种异体移植物存活数据。在这篇系统综述中，我们研究了VCA局部免疫抑制的临床前动物研究。

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来源
《Journal of plastic, reconstructive & aesthetic surgery: JPRAS》 |2021年第2期|共9页
作者
Safi Ali-Farid; Kauke Martin; Nelms Laurel; Palmer William Jackson; Tchiloemba Bianief; Kollar Branislav; Haug Valentin; Pomahac Bohdan;
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作者单位

Harvard Med Sch Brigham &

Womens Hosp Dept Surg Div Plast Surg 75 Francis St Boston MA 02115;

Harvard Med Sch Brigham &

Womens Hosp Dept Surg Div Plast Surg 75 Francis St Boston MA 02115;

Harvard Med Sch Brigham &

Womens Hosp Dept Surg Div Plast Surg 75 Francis St Boston MA 02115;

Harvard Med Sch Brigham &

Womens Hosp Dept Surg Div Plast Surg 75 Francis St Boston MA 02115;

Harvard Med Sch Brigham &

Womens Hosp Dept Surg Div Plast Surg 75 Francis St Boston MA 02115;

Harvard Med Sch Brigham &

Womens Hosp Dept Surg Div Plast Surg 75 Francis St Boston MA 02115;

Harvard Med Sch Brigham &

Womens Hosp Dept Surg Div Plast Surg 75 Francis St Boston MA 02115;

Harvard Med Sch Brigham &

Womens Hosp Dept Surg Div Plast Surg 75 Francis St Boston MA 02115;

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原文格式 PDF
正文语种 eng
中图分类整形外科学（修复外科学）;
关键词
Allotransplantation; VCA; CTA; Local; Immunosuppression; Targeted;

机译：同种异体移植;VCA;CTA;地方的免疫抑制;有针对性的;

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专利

1. Reviewing immunosuppressive regimens in animal models for vascularized composite allotransplantation [J] . Aline Yen Ling Wang1, Charles Yuen Yung Loh2 整形与美容研究(英文版) . 2018,第003期
2. Reviewing immunosuppressive regimens in animal models for vascularized composite allotransplantation [J] . Aline Yen Ling Wang, Charles Yuen Yung Loh 整形与美容研究（英文版） . 2018,第003期
3. Expanding the top rungs of the extremity reconstructive ladder:targeted muscle reinnervation,osseointegration,and vascularized composite allotransplantation [J] . Saïd C.Azoury, Andrew Bauder, Jason M.Souza, 整形与美容研究(英文版) . 2020,第002期
4. Expanding the top rungs of the extremity reconstructive ladder: targeted muscle reinnervation, osseointegration, and vascularized composite allotransplantation [J] . Saïd C. Azoury, Andrew Bauder, Jason M. Souza, 整形与美容研究（英文版） . 2020,第002期
5. PERIOPERATIVE RISK FACTORS FOR VASCULARIZED COMPOSITE ALLOTRANSPLANTATION: A SYSTEMATIC REVIEW AND PROPOSAL OF IDENTITY-DEFINING VCA [J] . HAINAN ZHU, XIAN WEI, WILLIAM LINEAWEAVER, Microsurgery. . 2014,第3期

机译：血管化复合异体移植的围手术期风险因素：系统的评价和确定身份的VCA的建议
6. Local Injections of Tacrolimus-loaded Hydrogel Reduce Systemic Immunosuppression-related Toxicity in Vascularized Composite Allotransplantation [J] . Dzhonova Dzhuliya V., Olariu Radu, Leckenby Jonathan, Transplantation: Official Journal of the Transplantation Society . 2018,第10期

机译：局部注射巨篷式水凝胶减少了血管化复合分征的全身免疫抑制相关毒性
7. Engineering a Future with VCA: Applying Genetic Circuits to Engineer Tissues for Vascularized Composite Allotransplantation [J] . Oliver Jeremie D., Duscher Dominik, Hu Michael S. Journal of plastic, reconstructive & aesthetic surgery: JPRAS . 2021,第1期

机译：使用VCA的工程来源：将遗传电路应用于血管化复合分征的工程组织
8. Induction of immune tolerance with heart-thymus composite allotransplantation in rats [C] . XIONG Hai-bo, XIA Sui-sheng, WEN Hao, Postdoctoral Symposium for Celebration of 20th Anniversary of the Foundation of Chinese Postdoctoral System; 2005; . 2005

机译：大鼠心胸复合同种异体移植诱导免疫耐受
9. Mycophenolic acid versus azathioprine in primary immunosuppression for kidney transplant recipients - Systematic review, meta-analysis, and meta-regression. [D] . Wagner, Martin. 2009

机译：麦考酚酸与硫唑嘌呤在肾移植受者初次免疫抑制中的作用-系统评价，荟萃分析和荟萃回归。
10. Abstract: 8.30 Subnormothermic Machine Perfusion (Snmp) With A Novel Hemoglobin-Based Oxygen Carrier (Hboc) Solution For Ex Vivo Preservation In Vascularized Composite Allotransplantation (Vca) [O] . Riccardo Schweizer, Sinan Oksuz, Barak Banan, 2017

机译：摘要：带有基于血红蛋白的新型氧气载体（Hboc）解决方案的8.30亚低温机器灌注（Snmp）用于血管化复合同种异体移植（Vca）的离体保存
11. Local Injections of Tacrolimus-loaded Hydrogel Reduce Systemic Immunosuppression-related Toxicity in Vascularized Composite Allotransplantation [O] . Dzhuliya V. Dzhonova, Radu Olariu, Jonathan Leckenby, 2018

机译：局部注射巨篷式水凝胶减少了血管化复合分征的全身免疫抑制相关毒性
12. Optimization of Delayed Tolerance Induction in Swine: A Clinically-Relevant Protocol for Immunosuppression-Free Vascularized Composite Allotransplantation. [R] . Cetrulo, C. L. 2017

机译：猪的延迟耐受诱导优化：免疫抑制血管化复合同种异体移植的临床相关方案。

Local immunosuppression in vascularized composite allotransplantation (VCA): A systematic review

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