Prediction of fetal status in fetaleonatal alloimmune thrombocytopenia (FNAIT)?

摘要

We read with interest the recent paper from Bertrand et al, which outlines an interesting topic regarding the use of antibody concentration as predictive parameter for FNAIT.Unfortunately, the number of subjects studied is very low. When the authors conclude that FNAIT is a severe disease and the first offspring is already at high risk, they base their analysis on 66 "index cases." A significant difference in antibody concentration between primagravidae and multigravidae, however, is concluded from the analysis of 54% (20/37) and 34% (10/29) of enrolled cases only. Selection criteria are not given.