Adrenal abscesses rarely occur in neonates and usually present with non-specific signs and symptoms. Prompt diagnosis requires an index of suspicion. We describe right-sided adrenal haemorrhage and abscess formation in a newborn with hypoxic-ischaemic encephalopathy following maternal post-partum haemorrhage and sepsis with Escherichia coli and Enterococcus faecalis. Percutaneous drainage of the abscess identified an E. coli isolate identical to that in the mother plus Candida albicans.
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