Isolation of Vibrio cholerae from neonates admitted to an urban diarrhoeal diseases hospital in Bangladesh.

摘要

BACKGROUND: Very little is known about Vibrio cholerae infection in neonates with diarrhoea. AIM: The aim was to examine the frequency of enteropathogenic bacteria, especially Vibrio cholerae, in stool specimens from neonates with diarrhoea. METHODS: We reviewed the hospital records of 240 neonates admitted with diarrhoea to the Dhaka Hospital of ICDDR,B: Centre for Health and Population Research, Dhaka, Bangladesh during January-December 2001. On admission, rectal swabs or stool specimens were plated directly onto taurocholate-tellurite-gelatin agar, Salmonella-Shigella agar and MacConkey's agar for culture of Vibrio cholerae, Shigella and Salmonella spp. RESULTS: A single bacterial enteric pathogen was detected in 71 neonates, multiple pathogens in 12, and stool samples of 157 neonates revealed no pathogen. The identified enteropathogens were as follows: V. cholerae in 42 neonates, Shigella spp in 22, Salmonella spp in 8, Aeromonas spp in 9 and Hafnia alvei in 2. CONCLUSION: V. cholerae is not uncommon in neonates presenting with diarrhoea in cholera-endemic countries.