Fine particulate matter (PM2.5) promotes IgE-mediated mast cell activation through ROS/Gadd45b/JNK axis

Wang Ying; Tang Ni; Mao Manyun; Zhou Youyou; Wu Yingfang; Li Juan; Zhang Wei; Peng Cong; Chen Xiang; Li Jie

首页> 外文期刊>Journal of dermatological science >Fine particulate matter (PM2.5) promotes IgE-mediated mast cell activation through ROS/Gadd45b/JNK axis

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Fine particulate matter (PM2.5) promotes IgE-mediated mast cell activation through ROS/Gadd45b/JNK axis

机译：细颗粒物质（PM2.5）通过ROS / GADD45B / JNK轴促进IgE介导的肥大细胞活化

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摘要

Background: Mast cells play an important role in allergic responses and persistently exposure to environmental fine particulate matter (PM2.5) exacerbates allergic diseases,but the details remained elucidative.

机译：背景：肥大细胞在过敏反应中起重要作用，长期暴露于环境细颗粒物（PM2.5）会加剧过敏性疾病，但具体细节尚不清楚。

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来源
《Journal of dermatological science》 |2021年第1期|共11页
作者
Wang Ying; Tang Ni; Mao Manyun; Zhou Youyou; Wu Yingfang; Li Juan; Zhang Wei; Peng Cong; Chen Xiang; Li Jie;
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作者单位

Cent South Univ Xiangya Hosp Dept Dermatol Changsha 410078 Peoples R China;

Cent South Univ Xiangya Hosp Dept Dermatol Changsha 410078 Peoples R China;

Cent South Univ Xiangya Hosp Dept Dermatol Changsha 410078 Peoples R China;

Cent South Univ Xiangya Hosp Dept Dermatol Changsha 410078 Peoples R China;

Cent South Univ Xiangya Hosp Dept Dermatol Changsha 410078 Peoples R China;

Cent South Univ Xiangya Hosp Dept Dermatol Changsha 410078 Peoples R China;

Cent South Univ Xiangya Hosp Inst Clin Pharmacol Changsha Peoples R China;

Cent South Univ Xiangya Hosp Dept Dermatol Changsha 410078 Peoples R China;

Cent South Univ Xiangya Hosp Dept Dermatol Changsha 410078 Peoples R China;

Cent South Univ Xiangya Hosp Dept Dermatol Changsha 410078 Peoples R China;

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原文格式 PDF
正文语种 eng
中图分类皮肤病学与性病学;
关键词
IgE-mediated mast cell activation; Particulate matter (PM2; 5); The ROS; Gadd45b; JNK axis;

机译：IgE介导的肥大细胞活化;颗粒物质（PM2;5）;ROS;GADD45B;JNK轴;

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专利

1. Fine Particulate Matter-Induced Exacerbation of Allergic Asthma via Activation of T-cell Immunoglobulin and Mucin Domain 1 [J] . Yun-Xia Zhao, Hui-Ran Zhang, Xiu-Na Yang, 中华医学杂志（英文版） . 2018,第020期
2. Visualizing Patterns and Differences in Fine Particulate Matter (PM2.5) Research Between the USA and China over Last 25 Years: A Bibliometric Analysis [J] . Shan De-xin, Gao Jia-nan, Liu Xiao, 东北农业大学学报（英文版） . 2020,第001期
3. Characteristics of Atmospheric Fine Particulate Matter (PM2.5) Induced Differentially Expressed Proteins Determined by Proteomics and Bioinformatics Analyses [J] . ZHENGxa0Kai, XUxa0Xinxa0Yun, CAIxa0Ying, 生物医学与环境科学（英文版） . 2020,第008期
4. Effects of the ambient fine particulate matter (PM2.5) exposure on urinary metabolic profiles in rats using UPLC-Q-TOF-MS [J] . Lin Zhang, Tengfei Xu, Zifeng Pi, 中国化学快报（英文版） . 2019,第001期
5. Fine particulate matter (PM2.5):The culprit for chronic lung diseases in China [J] . Tao Li, Rong Hu, Zi Chen, 慢性疾病与转化医学（英文） . 2018,第003期
6. TP53-dependent autophagy links the ATR-CHEK1 axis activation to proinflammatory VEGFA production in human bronchial epithelial cells exposed to fine particulate matter (PM2.5) [J] . Xu Xiuduan, Wang Hongli, Liu Shasha, Autophagy . 2016,第10期

机译：TP53依赖性自噬链接将ATR-Chek1轴激活链接到促进细颗粒物质（PM2.5）的人支气管上皮细胞中的促炎VEGFA生产
7. Fine particulate matter (PM2.5) enhances Fc epsilon RI-mediated signaling and mast cell function [J] . Jin Yuefei, Zhu Minghua, Guo Yanli, Cellular Signalling . 2019,第期

机译：细颗粒物质（PM2.5）增强FcεRI介导的信号传导和肥大细胞功能
8. Fine Particulate Matter (PM2.5) Promoted the Invasion of Lung Cancer Cells via an ARNT2/PP2A/STAT3/MMP2 Pathway (vol 14, pg 2172, 2018) [J] . Chen Zhongqi, Ji Ningfei, Wang Zhengxia, Journal of biomedical nanotechnology . 2019,第2期

机译：细颗粒物质（PM2.5）通过ARNT2 / PP2A / STAT3 / MMP2途径促进肺癌细胞的侵袭（Vol 14，PG 2172,2018）
9. Contribution of Aerosol Optical Depth (AOD) Fine Particulate Matter (PM2.5) Fused Surfaces in Assessing Risk of Respiratory-Cardiovascular Hospitalizations and Emergency Room Visits in Baltimore [C] . Hall E Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology . 2019

机译：在巴尔的摩评估呼吸心血管住院和急诊就诊风险的气溶胶光学厚度（AOD）细颗粒物（PM2.5）融合表面的贡献
10. Near-roadway Air Pollution: Evaluation of Fine Particulate Matter (PM2.5) and Ultrafine Particulate Matter (PM0.1) in Interior Alaska [D] . Kadir, Abdul. 2019

机译：近巷道空气污染：在内部阿拉斯加内部的细颗粒物（PM2.5）和超细颗粒物（PM0.1）的评价
11. TP53-dependent autophagy links the ATR-CHEK1 axis activation to proinflammatory VEGFA production in human bronchial epithelial cells exposed to fine particulate matter (PM2.5) [O] . Xiuduan Xu, Hongli Wang, Shasha Liu, 2016

机译：依赖于TP53的自噬将ATR-CHEK1轴激活与暴露于细颗粒物（PM2.5）的人支气管上皮细胞中促炎性VEGFA产生联系起来
12. Fine Particulate Matter (PM2.5) upregulates expression of Inflammasome NLRP1 via ROS/NF-κB signaling in HaCaT Cells [O] . Liu Dong, Ruiming Hu, Dandan Yang, 2020

机译：细颗粒物质（PM2.5）通过HACAT细胞中通过ROS / NF-κB信号传导来推动炎症组NLRP1的表达
13. COMPARATIVE EVALUATION OF AMBIENT FINE PARTICULATE MATTER (PM2.5) DATA OBTAINED FROM URBAN AND RURAL MONITORING SITES ALONG THE UPPER OHIO RIVER VALLEY [R] . 2004

机译：上奥克西河流域城市和农村监测站点获得的环境细颗粒物（pm2.5）数据的比较评价

Fine particulate matter (PM2.5) promotes IgE-mediated mast cell activation through ROS/Gadd45b/JNK axis

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