IL-12 and Mucosal CD14(+) Monocyte-Like Cells Induce IL-8 in Colonic Memory CD4(+) T Cells of Patients With Ulcerative Colitis but not Crohn's Disease

摘要

Background and Aims. CD14(+) mononuclear phagocytes [MNPs] and T cells infiltrate colon in ulcerative colitis [UC]. Here we investigated how CD14(+) MNPs and the cytokines they produce shape the colonic effector T cell profile.