Gut Microbiota-driven Drug Metabolism in Inflammatory Bowel Disease

Crouwel Femke; Buiter Hans J. C.; de Boer Nanne K.

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Gut Microbiota-driven Drug Metabolism in Inflammatory Bowel Disease

机译：肠道微生物群驱动的炎症性肠病药物代谢

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Background and Aims: The gut microbiota plays an important role in the metabolization and modulation of several types of drugs. With this study we aimed to review the literature relating to microbial drug metabolism of medication prescribed in inflammatory bowel disease [IBD] practice.

机译：背景与目的：肠道微生物群在几种药物的代谢和调节中起着重要作用。通过这项研究，我们旨在回顾与炎症性肠病（IBD）实践中处方药物的微生物药物代谢相关的文献。

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来源
《Journal of Crohn’s & colitis》 |2021年第2期|共9页
作者
Crouwel Femke; Buiter Hans J. C.; de Boer Nanne K.;
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作者单位

Vrije Univ Amsterdam Amsterdam Univ Med Ctr AG&

M Res Inst Dept Gastroenterol &

Hepatol;

Vrije Univ Amsterdam Amsterdam Univ Med Ctr Dept Clin Pharmacol &

Pharm Amsterdam Netherlands;

Vrije Univ Amsterdam Amsterdam Univ Med Ctr AG&

M Res Inst Dept Gastroenterol &

Hepatol;

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原文格式 PDF
正文语种 eng
中图分类杆菌传染病;
关键词
Inflammatory bowel disease; drug metabolism; microbiota;

机译：炎症性肠病;药物代谢;微生物群;
入库时间 2022-08-20 19:50:33

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1. Regulation of drug metabolism and toxicity by multiple factors of genetics,epigenetics,lncRNAs,gut microbiota,and diseases:a meeting report of the 21st International Symposium on Microsomes and Drug Oxidations（MDO） [J] . Ai-Ming Yu, Magnus Ingelman-Sundberg, Nathan J.Cherrington, 药学学报：英文版 . 2017,第002期
2. Regulation of drug metabolism and toxicity by multiple factors of genetics, epigenetics, lncRNAs,gut microbiota, and diseases: a meeting report of the 21st International Symposium on Microsomes and Drug Oxidations (MDO) [J] . Ai-Ming Yu, Curtis D.Klaassen, Aadra P.Bhatt, 药学学报（英文版） . 2017,第002期
3. Reply to the Letter: Gut Microbiota-mediated Pleiotropic Effects of Fucose Can Improve Inflammatory Bowel Disease by Modulating Bile Acid Metabolism and Enhancing Propionate Production [J] . Ke Jun, He Ruohang, Hou Xiaohua Inflammatory bowel diseases . 2021,第2期

机译：回复信件：通过调节胆汁酸性代谢和增强丙酸盐生产，肠道微生物膜介导的岩浆术的肺炎效应可以改善炎症性肠病
4. Gut Microbiota-Mediated Pleiotropic Effects of Fucose Can Improve Inflammatory Bowel Disease by Modulating Bile Acid Metabolism and Enhancing Propionate Production [J] . Sitkin Stanislav, Vakhitov Timur, Kononova Svetlana, Inflammatory bowel diseases . 2021,第2期

机译：肠道微生物膜介导的岩藻糖的脂肪效应可以通过调节胆汁酸代谢和增强丙种生产来改善炎症性肠病
5. Spp24 is associated with endocytic signalling, lipid metabolism, and discrimination of tissue integrity for ‘leaky-gut’ in inflammatory bowel disease [J] . Valerie C. Wasinger, Kenneth Lu, Yunki Y. Yau, Scientific reports. . 2020,第1期

机译：SPP24与内吞信号传导，脂质代谢和对炎症性肠病“泄漏肠道”的组织完整性相关联
6. Site-Directed Polymer-Drug Complexes for Modulating Gut Innate Immune System to Prevent/Treat Inflammatory Bowel Diseases(IBD) [C] . KesharwaniS., AhmadR., RajputM. Bioengineering and Translational Medicine Conference . 2018

机译：用于调节肠道肠道免疫系统的部位定向聚合物 - 药物复合物，以预防/治疗炎症性肠病（IBD）
7. Impact of Activated and Resting Mesenchymal Stem Cells on Immune Responses and Gut Microbiome and Immune Responses to Gut Bacteria in Dogs With Inflammatory Bowel Disease [D] . Soontararak, Sirikul. 2019

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8. Studies of gut mucosal protein synthesis in a non-steroidal anti-inflammatory drug (NSAID) model of inflammatory bowel disease. [O] . A K Banerjee, J S Marway, V R Preedy, 1992

机译：在炎症性肠病的非甾体抗炎药（NSAID）模型中研究肠粘膜蛋白合成。
9. Studies of gut mucosal protein synthesis in a non-steroidal anti-inflammatory drug (NSAID) model of inflammatory bowel disease. [O] . Banerjee, A K, Marway, J S, Preedy, V R, 1992

机译：在炎性肠病的非甾体抗炎药（NSAID）模型中研究肠粘膜蛋白合成。
10. Effects of Omega-3 Fatty Acids on Lipids and Glycemic Control in Type II Diabetes and the Metabolic Syndrome and on Inflammatory Bowel Disease, Rheumatoid Arthritis, Renal Disease, Systemic Lupus Erythematosus, and Osteoporosis Evidence Report/Technology [R] . Newberry, S. J., Gralnek, I., MacLean, C. H., 2004

机译：Omega-3脂肪酸对II型糖尿病和代谢综合征以及炎症性肠病，类风湿性关节炎，肾病，系统性红斑狼疮和骨质疏松症的血脂和血糖控制的影响证据报告/技术

Gut Microbiota-driven Drug Metabolism in Inflammatory Bowel Disease

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