Using etoposide plus dexamethasone-based regimens to treat nasal type extranodal natural killer/T-cell lymphoma-associated hemophagocytic lymphohistiocytosis

Wei Liqiang; Yang Lei; Cong Jia; Ye Jin; Li Xin; Yao Na; Yang Jing; Ding Jing; Wang Jingwen

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Using etoposide plus dexamethasone-based regimens to treat nasal type extranodal natural killer/T-cell lymphoma-associated hemophagocytic lymphohistiocytosis

机译：使用依托泊苷加上基于地塞米松的方案治疗鼻型外肌杀伤/ T细胞淋巴瘤相关的血小杂性淋巴管症

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Purpose Nasal type extranodal natural killer/T-cell lymphoma (ENKTL) can be associated with hemophagocytic lymphohistiocytosis (NK/T-LAHLH), which is a rare and fatal disease with no effective therapy. We evaluated whether etoposide + dexamethasone-based chemotherapy regimens might be useful for treating NK/T-LAHLH.

机译：目的鼻型结外自然杀伤细胞/T细胞淋巴瘤（ENKTL）可与噬血细胞性淋巴组织细胞增生症（NK/T-LAHLH）相关，这是一种罕见的致命疾病，没有有效的治疗方法。我们评估了依托泊苷+地塞米松为主的化疗方案是否有助于治疗NK/T-LAHLH。

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来源
《Journal of Cancer Research and Clinical Oncology》 |2021年第3期|共7页
作者
Wei Liqiang; Yang Lei; Cong Jia; Ye Jin; Li Xin; Yao Na; Yang Jing; Ding Jing; Wang Jingwen;
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作者单位

Capital Med Univ Beijing Tongren Hosp Dept Hematol 1 Dong Jiao Min Xiang St Beijing 100730;

Capital Med Univ Beijing Tongren Hosp Dept Hematol 1 Dong Jiao Min Xiang St Beijing 100730;

Capital Med Univ Beijing Tongren Hosp Dept Hematol 1 Dong Jiao Min Xiang St Beijing 100730;

Capital Med Univ Beijing Tongren Hosp Dept Hematol 1 Dong Jiao Min Xiang St Beijing 100730;

Capital Med Univ Beijing Tongren Hosp Dept Hematol 1 Dong Jiao Min Xiang St Beijing 100730;

Capital Med Univ Beijing Tongren Hosp Dept Hematol 1 Dong Jiao Min Xiang St Beijing 100730;

Capital Med Univ Beijing Tongren Hosp Dept Hematol 1 Dong Jiao Min Xiang St Beijing 100730;

Capital Med Univ Beijing Tongren Hosp Dept Hematol 1 Dong Jiao Min Xiang St Beijing 100730;

Capital Med Univ Beijing Tongren Hosp Dept Hematol 1 Dong Jiao Min Xiang St Beijing 100730;

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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词
Extranodal NK/T-cell lymphoma; nasal type; Hemophagocytic lymphohistiocytosis; Chemotherapy; Etoposide; Dexamethasone;

机译：外结NK / T细胞淋巴瘤;鼻型;血液活性淋巴管激菌症;化疗;依托普苷;地塞米松;

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专利

1. CD30 expression in extranodal natural killer/T-cell lymphoma, nasal type among 622cases of mature T-cell and natural killer-cell lymphoma at a single institution in South China [J] . Yanfen Feng, Huilan Rao, Yiyan Lei, 癌症（英文版） . 2017,第006期
2. Outcomes of patients treated with SVILE vs.P-GemOx for extranodal natural killer/T-cell lymphoma,nasal type:a prospective,randomized controlled study [J] . Liqiang Wei, Lei Yang, Jin Ye, 癌症生物学与医学：英文版 . 2020,第003期
3. Outcomes of patients treated with SVILE vs. P-GemOx for extranodal natural killer/T-cell lymphoma, nasal type: a prospective, randomized controlled study [J] . Liqiang Wei, Yiping Wu, Jingwen Wang, 癌症生物学与医学（英文版） . 2020,第003期
4. SVILE regimen, a combination of dexamethasone, vindesine, ifosfamide, pegaspargase, and etoposide, for treating relapsed/refractory extranodal natural killer/T-cell lymphoma, nasal type [J] . Wei Liqiang, Wang Liang, Cong Jia, Leukemia Research: A Forum for Studies on Leukemia and Normal Hemopoiesis . 2020,第1期

机译：Svile方案，地塞米松，Vindesine，Ifosfamide，Pegaspargase和etposide的组合，用于处理复发/难治性外杀蛋白，鼻淋巴瘤
5. Successful treatment of extranodal natural killer/T-cell lymphoma, nasal type, complicated by severe hemophagocytic syndrome, with dexamethasone, methotrexate, ifosfamide, L-asparaginase, and etoposide chemotherapy followed by autologous stem cell transplant. [J] . Inoue D, Nagai Y, Takiuchi Y, Leukemia and lymphoma . 2010,第4期

机译：地塞米松，甲氨蝶呤，异环磷酰胺，L-天冬酰胺酶和依托泊苷化疗成功地治疗了鼻外自然型结节性自然杀伤/ T细胞淋巴瘤，并发严重的噬血细胞综合征，并进行了自体干细胞移植。
6. Long-term outcomes of patients with newly diagnosed extranodal natural killer/T-cell lymphoma treated by etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin regimen: a single-institution experience. [J] . Huang H, Lin Z, Lin X, Leukemia and lymphoma . 2011,第6期

机译：依托泊苷，泼尼松，长春新碱，环磷酰胺和阿霉素治疗的新诊断的结外自然杀手/ T细胞淋巴瘤患者的长期结局：单机构经验。
7. Characterization of the Biological and Clinical Relevance of RUNX Genes in Natural Killer/T-Cell Lymphoma [D] . Selvarajan, Viknesvaran 2016

机译：天然杀手/ T细胞淋巴瘤中RUNX基因的生物学和临床意义的表征。
8. A phase II prospective study of the Sandwich protocol L-asparaginase cisplatin dexamethasone and etoposide chemotherapy combined with concurrent radiation and cisplatin in newly diagnosed I/II stage nasal type extranodal natural killer/T-cell lymphoma [O] . Ming Jiang, Li Zhang, Li Xie, 2017

机译：在新诊断的I / II期鼻腔类型结外自然杀伤/ T细胞淋巴瘤中对三明治方案L-天冬酰胺酶顺铂地塞米松和依托泊苷化学疗法同时进行放疗和顺铂联合进行的II期前瞻性研究
9. Hemophagocytic Syndrome in Early Stage Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type [O] . B. Chen, Y.X. Li, S.L. Wang, 2018

机译：早期血糖综合征在早期的外部杀伤/ T细胞淋巴瘤，鼻型
10. Natural Killer Cell Cytotoxicity and T-Cell Proliferation Is Enhanced byAvoidance Behavior. (Reannouncement with New Availability Information) [R] . Millar, D. B., Thomas, J. R., Pacheco, N. D., 1993

机译：通过避免行为增强自然杀伤细胞的细胞毒性和T细胞增殖。（重新公布新的可用性信息）

Using etoposide plus dexamethasone-based regimens to treat nasal type extranodal natural killer/T-cell lymphoma-associated hemophagocytic lymphohistiocytosis

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