Multimodal therapeutic approach in acute ischaemic stroke with real-time neurovascular monitoring.

摘要

Intravenously administeredtissue plasminogen activator (IV-TPA) induces thrombolysis and remains the only FDA-approved therapy for acute ischaemic stroke (IS) within the therapeutic time-window according to the current guidelines. However, significantly low recanalisation rates have been demonstrated with intravenous thrombolysis alone. Ultrasound monitoring during IV-TPA infusion1 and mechanical embolectomy2 have been reported to enhance the rates of arterial recanalisation. We report a patient with severe acute IS in whom the multimodal therapeutic approach resulted in an excellent recovery. Our patient who underwent continuous neurovascular monitoring and temporal sequence of clinical events in real-time has been described.