Novel Risk Loci Associated With Genetic Risk for Bipolar Disorder Among Han Chinese Individuals A Genome-Wide Association Study and Meta-analysis

Li Hui-Juan; Zhang Chen; Hui Li; Zhou Dong-Sheng; Li Yi; Zhang Chu-Yi; Wang Chuang; Wang Lu; Li Wenqiang; Yang Yongfeng; Qu Na; Tang Jinsong; He Ying; Zhou Jun; Yang Zihao; Li Xingxing; Cai Jun; Yang Lu; Chen Jun; Fan Weixing; Tang Wei; Tang Wenxin; Jia Qiu-Fang; Liu Weiqing; Zhuo Chuanjun; Song Xueqin; Liu Fang; Bai Yan; Zhong Bao-Liang; Zhang Shu-Fang; Chen Jing; Xia Bin; Lv Luxian; Liu Zhongchun; Hu Shaohua; Li Xiao-Yan; Liu Jie-Wei; Cai Xin; Yao Yong-Gang; Zhang Yuyanan; Yan Hao; Chang Suhua; Zhao Jing-Ping; Yue Wei-Hua; Luo Xiong-Jian; Chen Xiaogang; Xiao Xiao; Fang Yiru; Li Ming

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Novel Risk Loci Associated With Genetic Risk for Bipolar Disorder Among Han Chinese Individuals A Genome-Wide Association Study and Meta-analysis

机译：与汉族人中双相障碍遗传风险相关的新型风险基因群，一种基因组 - 宽协会研究和荟萃分析

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摘要

This genome-wide association study and trans-ancestry meta-analysis explores the genetic basis of bipolar disorder in a Han Chinese population and assesses shared bipolar disorder genetic risk between Han Chinese and European populations.

机译：这项全基因组关联研究和跨血统荟萃分析探索了汉族人群中双相情感障碍的遗传基础，并评估了汉族和欧洲人群中共有的双相情感障碍遗传风险。

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来源
《JAMA psychiatry》 |2021年第3期|共11页
作者
Li Hui-Juan; Zhang Chen; Hui Li; Zhou Dong-Sheng; Li Yi; Zhang Chu-Yi; Wang Chuang; Wang Lu; Li Wenqiang; Yang Yongfeng; Qu Na; Tang Jinsong; He Ying; Zhou Jun; Yang Zihao; Li Xingxing; Cai Jun; Yang Lu; Chen Jun; Fan Weixing; Tang Wei; Tang Wenxin; Jia Qiu-Fang; Liu Weiqing; Zhuo Chuanjun; Song Xueqin; Liu Fang; Bai Yan; Zhong Bao-Liang; Zhang Shu-Fang; Chen Jing; Xia Bin; Lv Luxian; Liu Zhongchun; Hu Shaohua; Li Xiao-Yan; Liu Jie-Wei; Cai Xin; Yao Yong-Gang; Zhang Yuyanan; Yan Hao; Chang Suhua; Zhao Jing-Ping; Yue Wei-Hua; Luo Xiong-Jian; Chen Xiaogang; Xiao Xiao; Fang Yiru; Li Ming;
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作者单位

Chinese Acad Sci Key Lab Anim Models &

Human Dis Mech Kunming Inst Zool Chinese Acad Sci &

Shanghai Jiao Tong Univ Shanghai Mental Hlth Ctr Clin Res Ctr Sch Med 600 S Wanping Rd;

Soochow Univ Suzhou Guangji Hosp Affiliated Guangji Hosp Suzhou Jiangsu Peoples R China;

Ningbo Kangning Hosp Dept Psychiat Ningbo Zhejiang Peoples R China;

Huazhong Univ Sci &

Technol Tongji Med Coll Affiliated Wuhan Mental Hlth Ctr Wuhan Hubei;

Chinese Acad Sci Key Lab Anim Models &

Human Dis Mech Kunming Inst Zool Chinese Acad Sci &

Ningbo Univ Sch Med Dept Pharmacol Ningbo Zhejiang Peoples R China;

Chinese Acad Sci Key Lab Anim Models &

Human Dis Mech Kunming Inst Zool Chinese Acad Sci &

Xinxiang Med Univ Henan Mental Hosp Affiliated Hosp 2 Xinxiang Henan Peoples R China;

Xinxiang Med Univ Henan Mental Hosp Affiliated Hosp 2 Xinxiang Henan Peoples R China;

Huazhong Univ Sci &

Technol Tongji Med Coll Affiliated Wuhan Mental Hlth Ctr Wuhan Hubei;

Zhejiang Univ Sir Run Run Shaw Hosp Sch Med Dept Psychiat Hangzhou Zhejiang Peoples R China;

Cent South Univ Xiangya Hosp 2 Dept Psychiat Changsha Hunan Peoples R China;

Cent South Univ Xiangya Hosp 2 Dept Psychiat Changsha Hunan Peoples R China;

Cent South Univ Xiangya Hosp 2 Dept Psychiat Changsha Hunan Peoples R China;

Ningbo Kangning Hosp Dept Psychiat Ningbo Zhejiang Peoples R China;

Shanghai Jiao Tong Univ Shanghai Mental Hlth Ctr Clin Res Ctr Sch Med 600 S Wanping Rd;

Shanghai Jiao Tong Univ Shanghai Mental Hlth Ctr Clin Res Ctr Sch Med 600 S Wanping Rd;

Shanghai Jiao Tong Univ Shanghai Mental Hlth Ctr Clin Res Ctr Sch Med 600 S Wanping Rd;

Jinhua Second Hosp Jinhua Zhejiang Peoples R China;

Wenzhou Med Univ Dept Psychiat Affiliated Kangning Hosp Wenzhou Zhejiang Peoples R China;

Hangzhou Seventh Peoples Hosp Hangzhou Zhejiang Peoples R China;

Soochow Univ Suzhou Guangji Hosp Affiliated Guangji Hosp Suzhou Jiangsu Peoples R China;

Kunming Med Univ Dept Psychiat Affiliated Hosp 1 Kunming Yunnan Peoples R China;

Tianjin Med Univ Nankai Univ Affiliated Tianjin Anding Hosp Mental Hlth Teaching Hosp Tianjin;

Zhengzhou Univ Affiliated Hosp 1 Zhengzhou Henan Peoples R China;

Kunming Med Univ Dept Psychiat Affiliated Hosp 1 Kunming Yunnan Peoples R China;

Kunming Med Univ Dept Psychiat Affiliated Hosp 1 Kunming Yunnan Peoples R China;

Huazhong Univ Sci &

Technol Tongji Med Coll Affiliated Wuhan Mental Hlth Ctr Wuhan Hubei;

Huazhong Univ Sci &

Technol Tongji Med Coll Affiliated Wuhan Mental Hlth Ctr Wuhan Hubei;

Huazhong Univ Sci &

Technol Tongji Med Coll Affiliated Wuhan Mental Hlth Ctr Wuhan Hubei;

Huazhong Univ Sci &

Technol Tongji Med Coll Affiliated Wuhan Mental Hlth Ctr Wuhan Hubei;

Xinxiang Med Univ Henan Mental Hosp Affiliated Hosp 2 Xinxiang Henan Peoples R China;

Wuhan Univ Renmin Hosp Dept Psychiat Wuhan Hubei Peoples R China;

Zhejiang Univ Affiliated Hosp 1 Dept Psychiat Sch Med Hangzhou Zhejiang Peoples R China;

Chinese Acad Sci Key Lab Anim Models &

Human Dis Mech Kunming Inst Zool Chinese Acad Sci &

Chinese Acad Sci Key Lab Anim Models &

Human Dis Mech Kunming Inst Zool Chinese Acad Sci &

Chinese Acad Sci Key Lab Anim Models &

Human Dis Mech Kunming Inst Zool Chinese Acad Sci &

Chinese Acad Sci Key Lab Anim Models &

Human Dis Mech Kunming Inst Zool Chinese Acad Sci &

Peking Univ Sixth Hosp Inst Mental Hlth Beijing Peoples R China;

Peking Univ Sixth Hosp Inst Mental Hlth Beijing Peoples R China;

Peking Univ Sixth Hosp Inst Mental Hlth Beijing Peoples R China;

Cent South Univ Xiangya Hosp 2 Dept Psychiat Changsha Hunan Peoples R China;

Peking Univ Sixth Hosp Inst Mental Hlth Beijing Peoples R China;

Chinese Acad Sci Key Lab Anim Models &

Human Dis Mech Kunming Inst Zool Chinese Acad Sci &

Cent South Univ Xiangya Hosp 2 Dept Psychiat Changsha Hunan Peoples R China;

Chinese Acad Sci Key Lab Anim Models &

Human Dis Mech Kunming Inst Zool Chinese Acad Sci &

Shanghai Jiao Tong Univ Shanghai Mental Hlth Ctr Clin Res Ctr Sch Med 600 S Wanping Rd;

Chinese Acad Sci Key Lab Anim Models &

Human Dis Mech Kunming Inst Zool Chinese Acad Sci &

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正文语种 eng
中图分类神经病学与精神病学;
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2. Genetic polymorphisms and gastric cancer risk: a comprehensive review synopsis from meta-analysis and genome-wide association studies [J] . Jie Tian, Guanchu Liu, Chunjian Zuo, 癌症生物学与医学：英文版 . 2019,第002期
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4. Association between PPARG genetic polymorphisms and ischemic stroke risk in a northern Chinese Han population: a case-control study [J] . Yan-Zhe Wang, He-Yu Zhang, Fang Liu, 中国神经再生研究（英文版） . 2019,第011期
5. Evaluating risk loci for schizophrenia distilled from genome-wide association studies in Han Chinese from central China [J] . L Ma, J Tang, D Wang, Molecular Psychiatry . 2013,第6期

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6. Genetic predictors of risk and resilience in psychiatric disorders: A cross-disorder genome-wide association study of functional impairment in major depressive disorder, bipolar disorder, and schizophrenia [J] . McgrathL.M., CornelisM.C., LeeP.H., American journal of medical genetics, Part B. Neuropsychiatric genetics: the official publication of the International Society of Psychiatric Genetics . 2013,第8期

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8. Genome-wide association analysis with matched samples discloses additional novel risk loci [C] . Jungsoo Gim, Sungkyoung Choi, Jongho Im, IEEE International Conference on Bioinformatics and Biomedicine . 2014

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9. Genetic Biomarkers of Psychiatric Disease: Discriminating Bipolar Disorder from Major Depressive Disorder with Polygenic Risk Scores [D] . ?Liebers, David T. 2020

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Novel Risk Loci Associated With Genetic Risk for Bipolar Disorder Among Han Chinese Individuals A Genome-Wide Association Study and Meta-analysis

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