DBU-CATALYZED HIGHLY EFFICIENT SYNTHESIS OF 1,4-DIHYDROPYRIDINE DERIVATIVES FROM ARYLIDENEMALONONITRILES AND β-ENAMINO IMIDES

摘要

Various 1,4-dihydropyridine derivatives were efficiently synthesized from arylidenemalononitriles and β-enamino imides using DBU(3 mol%)as the catalyst at room temperature.This mild,straightforward high-yielding protocol was atom-economy,time-economy,with a low catalyst load,and without the need for reflux.