Pattern Separation in the Human Hippocampus: Response to Quiroga

摘要

In a recent article [1], Quiroga argues that there is no pattern separation in the human hippocampus based on data from human single-neuron studies. Quiroga argues instead that the hippocampus codes memories by coactivation of invariant and context-independent engrams. We believe that both pattern separation and completion are important components of human memory, and that overlooked empirical studies and theoretical considerations fundamentally challenge the arguments posed.