A randomized phase II study of S-1 plus oral leucovorin versus S-1 monotherapy in patients with gemcitabine-refractory advanced pancreatic cancer

Ueno M.; Okusaka T.; Omuro Y.; Isayama H.; Fukutomi A.; Ikeda M.; Mizuno N.; Fukuzawa K.; Furukawa M.; Iguchi H.; Sugimori K.; Furuse J.; Shimada K.; Ioka T.; Nakamori S.; Baba H.; Komatsu Y.; Takeuchi M.; Hyodo I.; Boku N.

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A randomized phase II study of S-1 plus oral leucovorin versus S-1 monotherapy in patients with gemcitabine-refractory advanced pancreatic cancer

机译：S-1加口服亚叶酸钙与S-1单药治疗吉西他滨难治性晚期胰腺癌的随机II期研究

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摘要

We evaluated the efficacy and toxicity of adding oral leucovorin (LV) to S-1 when compared with S-1 monotherapy in patients with gemcitabine-refractory pancreatic cancer (PC).

机译：我们比较了吉西他滨难治性胰腺癌（PC）患者与S-1单药治疗相比，向S-1中添加口服亚叶酸（LV）的疗效和毒性。

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《Annals of oncology: official journal of the European Society for Medical Oncology》 |2016年第3期|共7页
作者
Ueno M.; Okusaka T.; Omuro Y.; Isayama H.; Fukutomi A.; Ikeda M.; Mizuno N.; Fukuzawa K.; Furukawa M.; Iguchi H.; Sugimori K.; Furuse J.; Shimada K.; Ioka T.; Nakamori S.; Baba H.; Komatsu Y.; Takeuchi M.; Hyodo I.; Boku N.;
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正文语种 eng
中图分类肿瘤学;
关键词
phase II study; S-1; leucovorin; gemcitabine-refractory pancreatic cancer; pancreatic resection; albumin;

机译：II期研究;S-1;亚叶酸钙;吉西他滨难治性胰腺癌;胰腺切除;白蛋白;

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1. A randomized phase II study of S-1 plus oral leucovorin versus S-1 monotherapy in patients with gemcitabine-refractory advanced pancreatic cancer [J] . Ueno M., Okusaka T., Omuro Y., Annals of oncology: official journal of the European Society for Medical Oncology . 2016,第3期

机译：S-1加口服亚叶酸钙与S-1单药治疗吉西他滨难治性晚期胰腺癌的随机II期研究
2. S-1 as monotherapy or in combination with leucovorin as second-line treatment in gemcitabine-refractory advanced pancreatic cancer: A randomized, open-label, Multicenter, Phase II study [J] . GeF., XuN., BaiY., The oncologist . 2014,第11期

机译：S-1单药治疗或联合亚叶酸治疗二线治疗吉西他滨难治性晚期胰腺癌：一项随机，开放标签，多中心，II期研究
3. S-1 as Monotherapy or in Combination With Leucovorin as Second-Line Treatment in Gemcitabine-Refractory Advanced Pancreatic Cancer: A Randomized, Open-Label, Multicenter, Phase II Study [J] . Fei Li, Feijiao Ge, Huayan Xu, The oncologist . 2014,第11期

机译：吉西他滨难治性晚期胰腺癌单药治疗或联合白细胞素二线治疗的S-1：一项随机，开放标签，多中心，II期研究
4. S-1/CDDP/Lentinan Combination Chemotherapy for Inoperable Advanced Gastric Cancer [C] . Shoichi Nagahashi, Hidekazu Suzuki, Toshifumi Hib International Gastric Cancer Congress . 2005

机译：S-1 / CDDP / Lentinan组合化疗，可管理的胃癌无法操作
5. A Study of Erlotinib Monotherapy and in Combination with Pembrolizumab in Previously Untreated Stage I-IIIA Non-small Cell Lung Cancer [D] . Liu, Qiong. 2021

机译：Erlotinib单疗法和蛋白质在先前未处理阶段I-IIIA非小细胞肺癌中的研究
6. A randomized phase II study of S-1 plus oral leucovorin versus S-1 monotherapy in patients with gemcitabine-refractory advanced pancreatic cancer [O] . M. Ueno, T. Okusaka, Y. Omuro, -1

机译：S-1加口服亚叶酸钙与S-1单药治疗吉西他滨难治性晚期胰腺癌的II期随机研究
7. S-1 monotherapy versus S-1 combination therapy in gemcitabine-refractory advanced pancreatic cancer [O] . Sheng Zhong, Shuai Qie, Liu Yang, 2017

机译：S-1单疗法与S-1组合治疗吉西滨 - 难治性晚期胰腺癌

A randomized phase II study of S-1 plus oral leucovorin versus S-1 monotherapy in patients with gemcitabine-refractory advanced pancreatic cancer

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