Approximation of emicizumab plasma levels in emergency situations. A practical approach

Pekrul Isabell; Pfrepper Christian; Calatzis Geli; Giebl Andreas; Siegemund Annelie; Gruetzner Stefanie; Spannagl Michael

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Approximation of emicizumab plasma levels in emergency situations. A practical approach

机译：紧急情况下eMicizumab等离子体水平的近似。一种实用的方法

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Introduction: A dedicated emicizumab assay based on the modified one-stage factor VIII (FVIII) assay (mOSA) is mainly available in haemophilia treatment centres (HTC). A method to estimate emicizumab plasma levels based on a widely available assay would be desirable, especially for emergency situations.

机译：导言：血友病治疗中心（HTC）主要提供一种基于改良单阶段因子VIII（FVIII）分析（mOSA）的专用伊米珠单抗分析。一种基于广泛可用的检测方法来估计伊米珠单抗血浆水平的方法是可取的，尤其是在紧急情况下。

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来源
《Haemophilia: the official journal of the World Federation of Hemophilia》 |2021年第2期|共7页
作者
Pekrul Isabell; Pfrepper Christian; Calatzis Geli; Giebl Andreas; Siegemund Annelie; Gruetzner Stefanie; Spannagl Michael;
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作者单位

Ludwig Maximilian Univ Munich Dept Anaesthesiol Ziemssenstr 1 D-80336 Munich Germany;

Univ Hosp Leipzig Div Haemostaseol Med Dept 1 Leipzig Germany;

Ludwig Maximilian Univ Munich Dept Transfus Med Cell Therapeut &

Haemostaseol Munich Germany;

Augsburg Univ Clin Inst Transfus Med &

Hemostaseol Augsburg Germany;

Univ Hosp Leipzig Div Haemostaseol Med Dept 1 Leipzig Germany;

Augsburg Univ Clin Inst Transfus Med &

Hemostaseol Augsburg Germany;

Ludwig Maximilian Univ Munich Dept Transfus Med Cell Therapeut &

Haemostaseol Munich Germany;

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原文格式 PDF
正文语种 eng
中图分类妇产科学;
关键词
bispecific antibody; blood coagulation tests; emergency; emicizumab; Haemophilia A; one-stage assay; urgent surgery;

机译：双特异性抗体;血液凝固试验;紧急;emicizumab;血友病A;单阶段测定;紧急手术;

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Approximation of emicizumab plasma levels in emergency situations. A practical approach

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