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Efficacy and safety of suprachoroidal triamcinolone injection in horses with poorly responsive equine recurrent uveitis

机译:Suprachoroidal Triamonolone注入马匹响应响应性较差的马发性葡萄膜炎的疗效和安全性

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摘要

Objective Equine recurrent uveitis (ERU), a chronic, immune-mediated intraocular inflammatory disease, is a common cause of blindness in horses. The severity and recurrent nature of ERU makes it difficult to treat with current therapeutics leading to a poor visual prognosis. The suprachoroidal space (SCS), a potential space between the choroid and sclera surrounding the ocular posterior segment, offers a promising alternative site for drug application to the eye. Corticosteroid administration within this space is hypothesized to be safe and effective at controlling intraocular inflammation, especially in horses with poorly responsive ERU.
机译:目的马复发性葡萄膜炎(ERU)是一种慢性、免疫介导的眼内炎症性疾病,是马致盲的常见原因。ERU的严重性和复发性使得目前的治疗方法难以治疗,导致视力预后不良。脉络膜上间隙(SCS)是眼后段周围脉络膜和巩膜之间的一个潜在间隙,为眼部用药提供了一个有希望的替代部位。在这个空间内使用皮质类固醇被认为是安全有效的,可以控制眼内炎症,尤其是对反应性较差的ERU马。

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