Heart Rate Variability and Heart Rate Turbulence in Patients with Hematologic Malignancies Subjected to High- Dose Chemotherapy in the Course of Hematopoietic Stem Cell Transplantation

摘要

BackgroundIn hematological malignancies, remissions and cures may be achieved by hematopoietic stem cell transplantation (HSCT) following high-dose chemotherapy (HDC). Cardiotoxicity of such therapy has not yet been fully elucidated. Noninvasive approaches allowing to evaluate an autonomic control of the heart function include analyses of both heart rate variability (HRV) and heart rate turbulence (HRT).