MRI-guided adaptive brachytherapy in locally advanced cervical cancer (EMBRACE-I): a multicentre prospective cohort study

Potter Richard; Tanderup Kari; Schmid Maximilian Paul; Jurgenliemk-Schulz Ina; Haie-Meder Christine; Fokdal Lars Ulrik; Sturdza Alina Emiliana; Hoskin Peter; Mahantshetty Umesh; Segedin Barbara; Bruheim Kjersti; Huang Fleur; Rai Bhavana; Cooper Rachel; Van der Steen-Banasik Elzbieta; Van Limbergen Erik; Pieters Bradley Rumwell; Tan Li-Tee; Nout Remi Abubakar; De Leeuw Astrid Agatha Catharina; Ristl Robin; Petric Primoz; Nesvacil Nicole; Kirchheiner Kathrin; Kirisits Christian; Lindegaard Jacob Christian

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MRI-guided adaptive brachytherapy in locally advanced cervical cancer (EMBRACE-I): a multicentre prospective cohort study

机译：MRI引导的适应性近距离放射治疗在局部晚期宫颈癌（接受-I）：多方形前瞻性队列研究

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Background The concept of the use of MRI for image-guided adaptive brachytherapy (IGABT) in locally advanced cervical cancer was introduced 20 years ago. Here, we report on EMBRACE-I, which aimed to evaluate local tumour control and morbidity after chemoradiotherapy and MRI-based IGABT.

机译：背景20年前，MRI用于局部晚期宫颈癌的图像引导自适应近距离放射治疗（IGABT）的概念被提出。在这里，我们报告了拥抱-I，其目的是评估放化疗和基于MRI的IGABT后的局部肿瘤控制和发病率。

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来源
《The lancet oncology》 |2021年第4期|共10页
作者
Potter Richard; Tanderup Kari; Schmid Maximilian Paul; Jurgenliemk-Schulz Ina; Haie-Meder Christine; Fokdal Lars Ulrik; Sturdza Alina Emiliana; Hoskin Peter; Mahantshetty Umesh; Segedin Barbara; Bruheim Kjersti; Huang Fleur; Rai Bhavana; Cooper Rachel; Van der Steen-Banasik Elzbieta; Van Limbergen Erik; Pieters Bradley Rumwell; Tan Li-Tee; Nout Remi Abubakar; De Leeuw Astrid Agatha Catharina; Ristl Robin; Petric Primoz; Nesvacil Nicole; Kirchheiner Kathrin; Kirisits Christian; Lindegaard Jacob Christian;
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作者单位

Med Univ Vienna Comprehens Canc Ctr Dept Radiat Oncol A-1090 Vienna Austria;

Aarhus Univ Hosp Dept Oncol Aarhus Denmark;

Med Univ Vienna Comprehens Canc Ctr Dept Radiat Oncol A-1090 Vienna Austria;

Univ Med Ctr Utrecht Dept Radiat Oncol Utrecht Netherlands;

Gustave Roussy Dept Radiotherapy Villejuif France;

Aarhus Univ Hosp Dept Oncol Aarhus Denmark;

Med Univ Vienna Comprehens Canc Ctr Dept Radiat Oncol A-1090 Vienna Austria;

Mt Vernon Hosp Mt Vernon Canc Ctr London England;

Homi Bhabha Natl Inst Tata Mem Ctr Mumbai Maharashtra India;

Inst Oncol Ljubljana Dept Radiotherapy Ljubljana Slovenia;

Oslo Univ Hosp Norwegian Radium Hosp Dept Oncol Oslo Norway;

Cross Canc Inst Dept Oncol Edmonton AB Canada;

Postgrad Inst Med Educ &

Res Dept Radiotherapy &

Oncol Chandigarh India;

St Amess Univ Hosp Leeds Canc Ctr Leeds W Yorkshire England;

Radiotherapiegrp Arnhem Dept Radiotherapy Arnhem Netherlands;

UZ Leuven Dept Radiat Oncol Leuven Belgium;

Univ Amsterdam Amsterdam Univ Med Ctr Acad Med Ctr Dept Radiat Oncol Amsterdam Netherlands;

Cambridge Univ Hosp Addenbrookes Hosp Dept Oncol Cambridge England;

Leiden Univ Dept Radiat Oncol Med Ctr Leiden Netherlands;

Univ Med Ctr Utrecht Dept Radiat Oncol Utrecht Netherlands;

Med Univ Vienna Ctr Med Stat Informat &

Intelligent Syst Vienna Austria;

Inst Oncol Ljubljana Dept Radiotherapy Ljubljana Slovenia;

Med Univ Vienna Comprehens Canc Ctr Dept Radiat Oncol A-1090 Vienna Austria;

Med Univ Vienna Comprehens Canc Ctr Dept Radiat Oncol A-1090 Vienna Austria;

Med Univ Vienna Comprehens Canc Ctr Dept Radiat Oncol A-1090 Vienna Austria;

Aarhus Univ Hosp Dept Oncol Aarhus Denmark;

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正文语种 eng
中图分类肿瘤学;
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1. A prospective study on radiofrequency ablation locally advanced pancreatic cancer [J] . Riccardo Casadei, Claudio Ricci, Raffaele Pezzilli, 国际肝胆胰疾病杂志（英文版） . 2010,第003期
2. Effect of preoperative hyperselective uterine arterial chemoembolization on the infiltrative growth of cancer cells in locally advanced cervical cancer [J] . Xiao-Hong Li, Li-Na Zhang 海南医科大学学报（英文版） . 2018,第011期
3. Effect of preoperative hyperselective uterine arterial chemoembolization on the infiltrative growth of cancer cells in locally advanced cervical cancer [J] . Xiao-Hong Li, Li-Na Zhang 海南医科大学学报(英文版) . 2018,第011期
4. High-dose-rate intraluminal brachytherapy during preoperative chemoradiation for locally advanced rectal cancers [J] . Mutahir, Ali, Tunio, 世界胃肠病学杂志：英文版 . 2010,第035期
5. Dose-volume effect relationships for late rectal morbidity in patients treated with chemoradiation and MRI-guided adaptive brachytherapy for locally advanced cervical cancer: Results from the prospective multicenter EMBRACE study [J] . Mazeron Renaud., Fokdal Lars U., Kirchheiner Kathrin, Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology . 2016,第3期

机译：放疗和MRI引导的自适应近距离放射治疗局部晚期宫颈癌患者晚期直肠癌发病率的量效关系：前瞻性多中心EMBRACE研究结果
6. Health related quality of life and patient reported symptoms before and during definitive radio(chemo)therapy using image-guided adaptive brachytherapy for locally advanced cervical cancer and early recovery A mono-institutional prospective study [J] . Kirchheiner Kathrin, Nout Rerni A., Czajka-Pepl Agnieszka, Gynecologic Oncology: An International Journal . 2015,第3期

机译：与健康相关的生活质量和患者报告的影像学适应性近距离放射治疗在放疗（化疗）之前和期间出现的症状，用于局部晚期宫颈癌和早期康复单机构前瞻性研究
7. Dose planning variations related to delineation variations in MRI-guided brachytherapy for locally advanced cervical cancer [J] . Brachytherapy . 2020,第2期

机译：与局部晚期宫颈癌MRI引导近距离放射治疗的描绘变异有关的剂量计划变化
8. Diffusion Weighted MRI (DWI) for Brachytherapy in Locally Advanced Cervical Cancer - Determining the Degree of Distortion at 1.5T and 3T MRI [C] . S. Haack, S.N. Jespersen, L. Fokdal, 15th Nordic-Baltic conference on biomedical engineering and medical physics . 2011

机译：扩散加权MRI（DWI）用于局部晚期宫颈癌的近距离放射治疗-确定1.5T和3T MRI的畸变程度
9. Adaptive Radiation Therapy Planning Using Fluorodeoxyglucose PET -- Locally Advanced Cervical Cancer. [D] . Mehta, Par. 2011

机译：使用氟脱氧葡萄糖PET进行的适应性放射治疗计划-局部晚期宫颈癌。
10. Treatment of locally advanced cervical cancer in a patient with a bicornuate uterus with MRI-guided intracavitary/interstitial brachytherapy [O] . Denise Fabian, Allison LaRocco, Meghan Olsen, 2019

机译：MRI引导下腔内/间质近距离放射疗法治疗双角子宫患者的局部晚期宫颈癌
11. Dose–volume effect relationships for late rectal morbidity in patients treated with chemoradiation and MRI-guided adaptive brachytherapy for locally advanced cervical cancer: Results from the prospective multicenter EMBRACE study [O] . Renaud Mazeron, Lars U. Fokdal, Kathrin Kirchheiner, 2016

机译：临床宫颈癌治疗和MRI引导适应性近距离放射治疗的患者晚直肠发病率的剂量效应关系：前瞻性多中心的研究结果
12. Millennium Cohort Study: A 21-Year Prospective Cohort Study of 140, 000 Military Personnel. [R] . Chesbrough, K. B., Ryan, M. A., Amoroso, P., 2001

机译：千禧年队列研究：对14万名军人进行的为期21年的前瞻性队列研究。

MRI-guided adaptive brachytherapy in locally advanced cervical cancer (EMBRACE-I): a multicentre prospective cohort study

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