Administration of Tranexamic Acid Improves Long-Term Outcomes in Total Knee Arthroplasty

摘要

Background: Blood transfusion in total knee arthroplasty (TKS) is associated with increased morbidity, including periprosthetic joint infection Tranexamic acid (TXA) reduces blood transfusion rates, but there is limited evidence demonstrating improved outcomes in TKA resulting from TXA administration. The objectives of this study are determining whether TXA is associated with decreased rate of PJI , decreased rate of outcomes associated with PJI, and whether there are differences in rates of adverse events.