Strategic achievement for the baseline separation of tocopherol isomers by integration of weak interaction sites on alternating copolymer

摘要

The complete baseline separation of vitamin E (tocopherol) isomers is described for the first time using newly developed alternating copolymer-silica (5 μm particle size) hybrids. The separation is driven by high molecular planarity (shape) selectivity due to multiple interactions with the integrated weak interaction sites towards the solute molecules.