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Crime scene investigation II: The effect of warfarin on bloodstain pattern analysis

机译:犯罪现场调查二:华法林对血迹分析的影响

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We explore for the first time the effect of medical drugs on Bloodstain Pattern Analysis (BPA). The widely administrated anticoagulant warfarin is examined with its effect on blood viscosity measured using a capillary tube viscometer over the range of 10~(-6) M to 10~(-4) M, representing therapeutic to fatal levels respectively. We find that the administration of therapeutic to fatal doses corresponds to a viscosity change of 3.6 to 20.4% respectively. Additionally the effect of warfarin on blood's surface tension, usually assumed to be constant, is examined over the therapeutic and fatal dosage range, which was found to result in a change of between 0.6 and 4.7% respectively. The observed variability's were integrated into previously derived BPA equations used for de-convoluting various parameters where convincing evidence is shown that drug contaminated blood induces a variation of 1.23 mm (5.93%) in the determined final stain diameter leading therefore to the possible misinterpretation of bloodstains found at Crime Scenes and consequently inaccuracies to occur in crime scene reconstruction. This work offers insight into whether medical drugs play a significant role in the possible misinterpretation of bloodstain evidence.
机译:我们首次探讨了药物对血迹图样分析(BPA)的影响。使用毛细管粘度计在10〜(-6)M至10〜(-4)M的范围内分别测量了从治疗到致命的水平,研究了广泛使用的抗凝华法林对血液粘度的影响。我们发现给予治疗剂量至致命剂量分别对应于3.6至20.4%的粘度变化。此外,在治疗剂量和致命剂量范围内检查了华法林对血液表面张力的影响(通常假定为恒定值),发现该剂量范围的变化分别在0.6%和4.7%之间。将观察到的变异性整合到先前推导的BPA方程中,该方程用于对各种参数进行反卷积,其中令人信服的证据表明,药物污染的血液在确定的最终污渍直径上引起1.23 mm(5.93%)的变化,因此可能会误解血迹在犯罪现场发现,因此在犯罪现场重建中不准确。这项工作提供了对药物是否可能在误解血迹证据中起重要作用的见解。

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