Thiophene anchored naphthalene derivative: Cr~(3+) selective turn-on fluorescent probe for living cell imaging

摘要

A naphthalene-based thiophene derivative (L) can act as a Cr~(3+) selective turn-on fluorescence probe in aqueous methanol. The structure of L has been established from different spectroscopic data and confirmed by X-ray crystallography. Under optimum conditions, the fluorescence intensity of L increases linearly from 1.0 x 10~(-6) to 52 x 10~(-6) M Cr~(3+) with a detection limit of 1.5 x 10~(-7) M. L also exhibits good cell permeability and can detect intracellular Cr~(3+) in contaminated living cells.