Synovial fluid concentrations of matrix Metalloproteinase-3 and Interluekin-6 following anterior cruciate ligament injury associate with gait biomechanics 6 months following reconstruction

Evans-Pickett A.; Longobardi L.; Spang J. T.; Creighton R. A.; Kamath G.; Davise-Wilson H. C.; Loeser R.; Blackburn J. T.; Pietrosimone B.

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Synovial fluid concentrations of matrix Metalloproteinase-3 and Interluekin-6 following anterior cruciate ligament injury associate with gait biomechanics 6 months following reconstruction

机译：基质金属蛋白酶-3的滑膜液体浓度-3术后前十字韧带损伤后的术后韧带损伤6个月后伴有步态生物力学

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Objective: To compare gait biomechanics 6 months following anterior cruciate ligament (ACL) reconstruction (ACLR) between patients with the highest and lowest concentrations of synovial fluid (SF) interleukin-6 (IL-6) and matrix metalloproteinase-3 (MMP-3), as well as compared to uninjured controls.

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来源
《Osteoarthritis and cartilage 》 |2021年第7期| 共14页
作者
Evans-Pickett A.; Longobardi L.; Spang J. T.; Creighton R. A.; Kamath G.; Davise-Wilson H. C.; Loeser R.; Blackburn J. T.; Pietrosimone B.;
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作者单位

Univ N Carolina Dept Exercise &

Sport Sci MOTION Sci Inst Chapel Hill NC 27515 USA;

Univ N Carolina Thurston Arthrit Res Ctr Chapel Hill NC 27599 USA;

Univ N Carolina Sch Med Dept Orthopaed Chapel Hill NC 27599 USA;

Univ N Carolina Sch Med Dept Orthopaed Chapel Hill NC 27599 USA;

Univ N Carolina Sch Med Dept Orthopaed Chapel Hill NC 27599 USA;

Univ N Carolina Dept Exercise &

Sport Sci MOTION Sci Inst Chapel Hill NC 27515 USA;

Univ N Carolina Thurston Arthrit Res Ctr Chapel Hill NC 27599 USA;

Univ N Carolina Dept Exercise &

Sport Sci MOTION Sci Inst Chapel Hill NC 27515 USA;

Univ N Carolina Dept Exercise &

Sport Sci MOTION Sci Inst Chapel Hill NC 27515 USA;

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原文格式 PDF
正文语种 eng
中图分类骨科学（运动系疾病、矫形外科学） ;
关键词
Biomarkers; Inflammation; ACL; Posttraumatic osteoarthritis; Knee;

机译：生物标志物;炎症;ACL;术后骨关节炎;膝盖;

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专利

1. Does age, time since injury and meniscal injury affect short term functional outcomes in arthroscopic single bundle anterior cruciate ligament reconstruction? [J] . Udit Kumar Biswal, Gopisankar Balaji, Sandeep Nema, 中华创伤杂志（英文版） . 2018 ,第001期
2. Effect of anterior cruciate ligament reconstruction on biomechanical features of knee in level walking： a meta-analysis [J] . SHI Dong-liang, WANG Yu-bin, AI Zi-sheng 中华医学杂志：英文版 . 2010 ,第021期
3. Effect of anterior cruciate ligament reconstruction on biomechanical features of knee in level walking: a meta-analysis [J] . SHI Dong-liang, WANG Yu-bin, AI Zi-sheng 中华医学杂志（英文版） . 2010 ,第021期
4. Biomechanical effects of manipulating peak vertical ground reaction force throughout gait in individuals 6-12 months after anterior cruciate ligament reconstruction [J] . Clinical biomechanics . 2020 ,第期

机译：在12-12个月内在胎儿韧带重建后6-12个月在整个步态中操纵峰值垂直接地反作用力的生物力学效应
5. FRONTAL PLANE KINEMATICS DURING WALKING GAIT ASSOCIATE WITH INCREASED SERUM CONCENTRATION OF AGGRECAN BREAKDOWN, BUT NOT TYPE II COLLAGEN BREAKDOWN, IN PATIENTS FOLLOWING ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION [J] . Harkey M. S., Luc B. A., Frank B. S., Osteoarthritis and cartilage . 2015 ,第Suppla2期

机译：在进行前交叉韧带重建的患者中，行进步态过程中的前线运动与血清总凝集素升高（而非II型胶原分解素）相关
6. FRONTAL PLANE KINEMATICS DURING WALKING GAIT ASSOCIATE WITH INCREASED SERUM CONCENTRATION OF AGGRECAN BREAKDOWN, BUT NOT TYPE II COLLAGEN BREAKDOWN, IN PATIENTS FOLLOWING ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION [J] . Harkey M. S., Luc B. A., Frank B. S., Osteoarthritis and cartilage . 2015 ,第Suppla2期

机译：步行步态期间的正面平面运动学随着血清浓度的血清浓度增加，但不是II型胶原蛋白崩溃，在患者患者后十字韧带重建
7. A biomechanical interpretation of the non-contact anterior cruciate ligament injury [C] . Thambyah Ashvin 2012 IEEE EMBS Conference on Biomedical Engineering and Sciences. . 2012

机译：非接触式前交叉韧带损伤的生物力学解释
8. Neuromuscular control after injury to the knee: An anterior cruciate ligament injury and reconstruction model. [D] . Hiemstra, Laurie Anne. 2003

机译：膝关节损伤后的神经肌肉控制：前十字韧带损伤和重建模型。
9. Higher aggrecan 1-F21 epitope concentration in synovial fluid early after anterior cruciate ligament injury is associated with worse knee cartilage quality assessed by gadolinium enhanced magnetic resonance imaging 20 years later [O] . Paul Neuman, Staffan Larsson, L. Stefan Lohmander, 2020

机译：在前十字架韧带损伤后在肾上腺韧带损伤早期较高的骨液1-F21表位浓度与钆增强磁共振成像评估的更差的膝关节软骨质量相关
10. Frontal plane kinematics during walking gait associate with increased serum concentration OF aggrecan breakdown, but not type II collagen breakdown, in patients following anterior cruciate ligament reconstruction [O] . Harkey M.S., Luc B.A., Frank B.S., 2015

机译：前交叉韧带重建术后患者行走步态的额面运动学与血清聚集蛋白聚糖分解的浓度增加相关，但与II型胶原蛋白分解无关
11. Gender Differences in Anterior Cruciate Ligament injury Vary With Activity: Epidemiology of Anterior Cruciate Ligament Injuries in a Young, Athletic Population. [R] . Mountcastle, S. B., Posner, M., Kragh Jr, J. F., 2007

机译：前交叉韧带损伤的性别差异与活动变化：年轻，运动人群前交叉韧带损伤的流行病学。

Synovial fluid concentrations of matrix Metalloproteinase-3 and Interluekin-6 following anterior cruciate ligament injury associate with gait biomechanics 6 months following reconstruction

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