MNS1 promotes hepatocarcinogenesis and metastasis via activating PI3K/AKT by translocating beta-catenin and predicts poor prognosis

摘要

Background & Aims Hepatocellular carcinoma (HCC) is a fatal disease characterized by vast molecular heterogeneity. Although major advances in tumour genetics has led to the identification of new biomarkers, the prognosis of patients with HCC remains dismal.