Changing Paradigms in Acute Kidney Injury: From Mechanisms to Management

摘要

Recent advances in the field of acute kidney injury (AKI) have provided key insights into understanding the mechanisms and pathways of AKI and its effects on other organs. Biomarkers have been identified that have provided new tools and techniques to characterize this disorder and facilitate point-of-care testing. Multiple underlying mechanisms contribute to the pathophysiology of AKI including genetic and epigenetic modifications, environmental influences and, more importantly, inherent mechanisms within the kidney offer challenging perspectives for clinical and translational research. This issue summarizes proceedings from the 6th University of Alabama at Birmingham (UAB)-University of California San Diego (UCSD) O'Brien Core Center for AKI Research symposium held during the 21st Annual Continuous Renal Replacement Therapy meeting in San Diego, California, USA, on Tuesday, February 16, 2016.