Characterizing the portability of phage-encoded homologous recombination proteins

Filsinger Gabriel T.; Wannier Timothy M.; Pedersen Felix B.; Lutz Isaac D.; Zhang Julie; Stork Devon A.; Debnath Anik; Gozzi Kevin; Kuchwara Helene; Volf Verena; Wang Stan; Rios Xavier; Gregg Christopher J.; Lajoie Marc J.; Shipman Seth L.; Aach John; Laub Michael T.; Church George M.

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Characterizing the portability of phage-encoded homologous recombination proteins

机译：表征噬菌体编码的同源重组蛋白的可移植性

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Bacteriophage single-stranded DNA annealing proteins (SSAPs) interact with the C termini of single-stranded binding proteins in host bacteria, a finding that enables engineering of enhanced SSAP portability and DNA recombineering activities.

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《Nature chemical biology》 |2021年第4期|共19页
作者
Filsinger Gabriel T.; Wannier Timothy M.; Pedersen Felix B.; Lutz Isaac D.; Zhang Julie; Stork Devon A.; Debnath Anik; Gozzi Kevin; Kuchwara Helene; Volf Verena; Wang Stan; Rios Xavier; Gregg Christopher J.; Lajoie Marc J.; Shipman Seth L.; Aach John; Laub Michael T.; Church George M.;
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Harvard Med Sch Dept Syst Biol Boston MA 02115 USA;

Harvard Univ Wyss Inst Biol Inspired Engn Cambridge MA 02138 USA;

Univ Southern Denmark Dept Biochem &

Mol Biol Odense Denmark;

Univ Washington Inst Prot Design Seattle WA 98195 USA;

MIT Dept Math Cambridge MA 02139 USA;

Harvard Univ Wyss Inst Biol Inspired Engn Cambridge MA 02138 USA;

Harvard Med Sch Dept Genet Boston MA 02115 USA;

MIT Dept Biol Cambridge MA USA;

Harvard Med Sch Dept Genet Boston MA 02115 USA;

Harvard Univ Wyss Inst Biol Inspired Engn Cambridge MA 02138 USA;

Harvard Univ Wyss Inst Biol Inspired Engn Cambridge MA 02138 USA;

Harvard Med Sch Dept Genet Boston MA 02115 USA;

Harvard Med Sch Dept Genet Boston MA 02115 USA;

Harvard Med Sch Dept Genet Boston MA 02115 USA;

Gladstone Inst San Francisco CA USA;

Harvard Med Sch Dept Genet Boston MA 02115 USA;

MIT Dept Biol Cambridge MA USA;

Harvard Univ Wyss Inst Biol Inspired Engn Cambridge MA 02138 USA;

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正文语种 eng
中图分类生物化学;
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专利

1. Effects of serum containing natural cerebrolysin on glucose-regulated protein 78 and CCAAT enhancer-binding protein homologous protein expression in neuronal PC12 cells following tunicamycin-induced endoplasmic reticulum stress [J] . Zhengzhi Wu, Ming Li, Andrew C.J. HuangO, 中国神经再生研究（英文版） . 2009,第002期
2. The cancer-testis gene, MEIOB, sensitizes triple-negative breast cancer to PARP1 inhibitors by inducing homologous recombination deficiency [J] . Yayun Gu, Hongxia Ma, Hongxia Wang, 癌症生物学与医学（英文版） . 2021,第001期
3. The cancer-testis gene,MEIOB,sensitizes triple-negative breast cancer to PARP1 inhibitors by inducing homologous recombination deficiency [J] . Yayun Gu, Cheng Wang, Rongxuan Zhu, 癌症生物学与医学：英文版 . 2021,第001期
4. The mutational pattern of homologous recombination (HR)-associated genes and its relevance to the immunotherapeutic response in gastric cancer [J] . Yue Fan, Lan Zheng, Haifeng Ying, 癌症生物学与医学（英文版） . 2020,第004期
5. Combining recombineering and ends-out homologous recombination to systematically characterize Drosophila gene families [J] . Chih-Chiang Chan, Shane Scoggin, P. Robin Hiesinger, Communicative & Integrative Biology . 2012,第2期

机译：结合重组和末端同源重组系统地表征果蝇基因家族
6. Schizosaccharomyces pombe Cds1Chk2 regulates homologous recombination at stalled replication forks through the phosphorylation of recombination protein Rad60. [J] . Miyabe I, Morishita T, Shinagawa H, Journal of Cell Science . 2009,第20期

机译：粟酒裂殖酵母Cds1Chk2通过重组蛋白Rad60的磷酸化调节停滞的复制叉处的同源重组。
7. HDF1, A YEAST KU-PROTEIN HOMOLOGUE, IS INVOLVED IN ILLEGITIMATE RECOMBINATION, BUT NOT IN HOMOLOGOUS RECOMBINATION [J] . Tsukamoto Y, Kato J, Ikeda H Nucleic Acids Research . 1996,第11期

机译：酵母KU蛋白同源物HDF1参与非法重组，但不参与同源重组
8. Comparative genomics revealed a novel DNA-binding regulatory protein involved in homologous recombination in bacteria [C] . Yang Gao, Yan Zhang 2011 IEEE International Conference on Systems Biology . 2011

机译：比较基因组学揭示了一种新型的DNA结合调节蛋白，参与细菌的同源重组
9. New Protein Systems for Homologous Recombination-based DNA Engineering in Bacteria [D] . Chen, Wenyang 2010

机译：用于细菌中基于同源重组的DNA工程的新蛋白质系统
10. Combining recombineering and ends-out homologous recombination to systematically characterize Drosophila gene families [O] . Chih-Chiang Chan, Shane Scoggin, P. Robin Hiesinger, 2012

机译：结合重组和末端同源重组系统地表征果蝇基因家族
11. The Mitochondrial DNA (mtDNA)-Associated Protein SWIB5 Influences mtDNA Architecture and Homologous Recombination. : The Mitochondrial DNA (mtDNA)-Associated Protein SWIB5 Influences mtDNA Architecture and Homologous Recombination. [O] . Blomme, Jonas, Van Aken, Olivier, Van Leene, Jelle, 2017

机译：线粒体DNA（mtDNA）相关蛋白SWIB5影响mtDNA结构和同源重组。：线粒体DNA（mtDNA）相关蛋白SWIB5影响mtDNA的结构和同源重组。
12. Inhibition of 53BP1: Potential for Restoring Homologous Recombination In Ovarian Cancer Cells. [R] . Botuyan, M. V. 2017

机译：抑制53Bp1：恢复卵巢癌细胞同源重组的潜力。

Characterizing the portability of phage-encoded homologous recombination proteins

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