Plasmodium vivax malaria-associated hemophagocytic lymphohistiocytosis in a young man with pancytopenia and fever.

摘要

Pancytopenia in a febrile patient may be the manifestation of bone marrow (BM) suppression induced by aplastic anemia, hematologic malignancies, metastatic cancer, infection, or inflammation [1]. Hemophagocytic lympho-histiocytosis (HLH), a rare cause of pancytopenia and fever, is triggered by genetic predisposition, malignancy, or infection by viruses, bacteria, or parasites [2-4]. Malaria has been found to cause infection-associated HLH [3, 5-8]. We describe a 22-year-old man with Plasmodium vivax-associated HLH.